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Suppliers for
Shp099 hydrochloride
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Properties | CAS |
1801747-11-4 |
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4 Registered suppliers
More details are to be found here
More details are to be found here
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Description : SHP099 is a potent, selective, orally bioavailable, and efficacious SHP2 inhibitor (IC50 value 0.071 μM) that stabilizes SHP2 in an auto-inhibited conformation. SHP099 suppresses signaling through the Ras-ERK pathway and blocks the proliferation of receptor tyrosine kinase-driven human cancer cells in vitro and in vivo. Molecular Formula : C16H20Cl3N5 Canonical SMILES : NC1=NC(N2CCC(C)(N)CC2)=CN=C1C3=CC=CC(Cl)=C3Cl.[H]Cl InChI : 1S/C16H19Cl2N5.ClH/c1-16(20)5-7-23(8-6-16)12-9-21-14(15(19)22-12)10-3-2-4-11(17)13(10)18;/h2-4,9H,5-8,20H2,1H3,(H2,19,22);1H InChIKey : KHQHYRFUYAXWOQ-UHFFFAOYSA-N Appearance : Yellow solid powder Storage : Store in a cool and dry place (or refer to the Certificate of Analysis). Synonyms : 6-(4-amino-4-methylpiperidin-1-yl)-3-(2,3-dichlorophenyl)pyrazin-2-amine hydrochloride; SHP099; SHP-099; SHP 099. SHP-099 hydrochloride, SHP-099 HCl.
More details are to be found here
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Last update 2024-05-10
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