BGC > Product Search > PF-06282999 | 1435467-37-0

Molecular Formula: C13H12ClN3O3S
Molecular Weight: 325.77068

Molecular Formula: C13H12ClN3O3S
Molecular Weight: 325.77068

Description :
PF-06282999 is a selective myeloperoxidase Inhibitor originate by Pfizer. It showed good oral pharmacokinetics in preclinical species and robust irreversible inhibition of plasma MPO activity. In Mar 2015, Pfizer terminated phase I trial for the treatment of Acute coronary syndromes in Healthy volunteers in USA.

• Molecular Weight :325.77
• Purity :98%

Molecular Formula :
C13H12ClN3O3S
Canonical SMILES :
COc1ccc(Cl)cc1C2=CC(=O)NC(=S)N2CC(=O)N
InChI :
1S/C13H12ClN3O3S/c1-20-10-3-2-7(14)4-8(10)9-5-12(19)16-13(21)17(9)6-11(15)18/h2-5H,6H2,1H3,(H2,15,18)(H,16,19,21)
InChIKey :
ICYNYWFGIDGBRD-UHFFFAOYSA-N
Solubility :
DMSO: ≥ 32 mg/mL
Appearance :
Powder
Application :
Acute coronary syndromes
Storage : -20°C Freezer
Synonyms :
PF-06282999; PF06282999; PF06282999. 2-(6-(5-chloro-2-methoxyphenyl)-4-oxo-2-thioxo-3,4-dihydropyrimidin-1(2H)-yl)acetamide

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