BGC > Product Search > Tizoxanide

Molecular Formula: C10H7N3O4S
Molecular Weight: 265.24528

Description :
Tizoxanide is the active metabolite of nitazoxanide, an anti-infective that has been approved for the treatment of diarrhea caused by Giardia lamblia or Crytosporidium parvum. Tizoxanide is active against anaerobic bacteria, protozoan parasites, and viruses. It reduces the growth of the disease-causing parasites, L. mexicana and T. cruzi, in vitro (IC50s = 6.2 and 17.5 μM, respectively), inhibits influenza A replication (EC50s = 0.3-1 μM)3, and inhibits hepatitis B and hepatitis C virus replication (EC50s both = 0.15 μM).

• Molecular Weight :265.25
• Melting Point :> 240 °C (dec)
• Purity :> 98%

Molecular Formula :
C10H7N3O4S
Canonical SMILES :
C1=CC=C(C(=C1)C(=O)NC2=NC=C(S2)[N+](=O)[O-])O
InChI :
InChI=1S/C10H7N3O4S/c14-7-4-2-1-3-6(7)9(15)12-10-11-5-8(18-10)13(16)17/h1-5,14H,(H,11,12,15)
InChIKey :
FDTZUTSGGSRHQF-UHFFFAOYSA-N
Solubility :
10 mM in DMSO
Appearance :
White to Off-white Solid
Application :
Anti-Infective Agents
Storage : - 20 °C
Synonyms :
TIZ; NSC-697856; NSC697856; NSC697856; Tizoxanide; Desacetylnitazoxanide; Desacetyl-nitazoxanide.

More details are to be found here

Description :
Tizoxanide is the active metabolite of nitazoxanide, an anti-infective that has been approved for the treatment of diarrhea caused by Giardia lamblia or Crytosporidium parvum. Tizoxanide is active against anaerobic bacteria, protozoan parasites, and viruses. It reduces the growth of the disease-causing parasites, L. mexicana and T. cruzi, in vitro (IC50s = 6.2 and 17.5 μM, respectively), inhibits influenza A replication (EC50s = 0.3-1 μM)3, and inhibits hepatitis B and hepatitis C virus replication (EC50s both = 0.15 μM).

• Molecular Weight :265.25
• Melting Point :> 240 °C (dec)
• Purity :> 98%

Molecular Formula :
C10H7N3O4S
Canonical SMILES :
C1=CC=C(C(=C1)C(=O)NC2=NC=C(S2)[N+](=O)[O-])O
InChI :
InChI=1S/C10H7N3O4S/c14-7-4-2-1-3-6(7)9(15)12-10-11-5-8(18-10)13(16)17/h1-5,14H,(H,11,12,15)
InChIKey :
FDTZUTSGGSRHQF-UHFFFAOYSA-N
Solubility :
10 mM in DMSO
Appearance :
White to Off-white Solid
Application :
Anti-Infective Agents
Storage : - 20 °C
Synonyms :
TIZ; NSC-697856; NSC697856; NSC697856; Tizoxanide; Desacetylnitazoxanide; Desacetyl-nitazoxanide.

More details are to be found here

Description :
Tizoxanide is the active metabolite of nitazoxanide, an anti-infective that has been approved for the treatment of diarrhea caused by Giardia lamblia or Crytosporidium parvum. Tizoxanide is active against anaerobic bacteria, protozoan parasites, and viruses. It reduces the growth of the disease-causing parasites, L. mexicana and T. cruzi, in vitro (IC50s = 6.2 and 17.5 μM, respectively), inhibits influenza A replication (EC50s = 0.3-1 μM)3, and inhibits hepatitis B and hepatitis C virus replication (EC50s both = 0.15 μM).

• Molecular Weight :265.25
• Melting Point :> 240 °C (dec)
• Purity :> 98%

Molecular Formula :
C10H7N3O4S
Canonical SMILES :
C1=CC=C(C(=C1)C(=O)NC2=NC=C(S2)[N+](=O)[O-])O
InChI :
InChI=1S/C10H7N3O4S/c14-7-4-2-1-3-6(7)9(15)12-10-11-5-8(18-10)13(16)17/h1-5,14H,(H,11,12,15)
InChIKey :
FDTZUTSGGSRHQF-UHFFFAOYSA-N
Solubility :
10 mM in DMSO
Appearance :
White to Off-white Solid
Application :
Anti-Infective Agents
Storage : - 20 °C
Synonyms :
TIZ; NSC-697856; NSC697856; NSC697856; Tizoxanide; Desacetylnitazoxanide; Desacetyl-nitazoxanide.

More details are to be found here

Description :
Tizoxanide is the active metabolite of nitazoxanide, an anti-infective that has been approved for the treatment of diarrhea caused by Giardia lamblia or Crytosporidium parvum. Tizoxanide is active against anaerobic bacteria, protozoan parasites, and viruses. It reduces the growth of the disease-causing parasites, L. mexicana and T. cruzi, in vitro (IC50s = 6.2 and 17.5 μM, respectively), inhibits influenza A replication (EC50s = 0.3-1 μM)3, and inhibits hepatitis B and hepatitis C virus replication (EC50s both = 0.15 μM).

• Molecular Weight :265.25
• Melting Point :> 240 °C (dec)
• Purity :> 98%

Molecular Formula :
C10H7N3O4S
Canonical SMILES :
C1=CC=C(C(=C1)C(=O)NC2=NC=C(S2)[N+](=O)[O-])O
InChI :
InChI=1S/C10H7N3O4S/c14-7-4-2-1-3-6(7)9(15)12-10-11-5-8(18-10)13(16)17/h1-5,14H,(H,11,12,15)
InChIKey :
FDTZUTSGGSRHQF-UHFFFAOYSA-N
Solubility :
10 mM in DMSO
Appearance :
White to Off-white Solid
Application :
Anti-Infective Agents
Storage : - 20 °C
Synonyms :
TIZ; NSC-697856; NSC697856; NSC697856; Tizoxanide; Desacetylnitazoxanide; Desacetyl-nitazoxanide.

More details are to be found here