BGC > Product Search > Teriflunomide

Description :
Teriflunomide, the active metabolite of leflunomide, is an immunomodulatory drug inhibiting pyrimidine de novo synthesis by blocking the enzyme dihydroorotate dehydrogenase. It inhibits rapidly dividing cells, including activated T cells, and tyrosine kinase enzymes.

• Molecular Weight :270.21
• Boiling Point :410.8±45.0°C (Predicted)
• Melting Point :229-232°C
• Purity :> 98%

Molecular Formula :
C12H9F3N2O2
Canonical SMILES :
CC(=C(C#N)C(=O)NC1=CC=C(C=C1)C(F)(F)F)O
InChI :
InChI=1S/C12H9F3N2O2/c1-7(18)10(6-16)11(19)17-9-4-2-8(3-5-9)12(13,14)15/h2-5,18H,1H3,(H,17,19)/b10-7-
InChIKey :
UTNUDOFZCWSZMS-YFHOEESVSA-N
Solubility :
Soluble in DMSO (Slightly), Methanol (Sparingly)
Appearance :
White to Off-white Solid
Application :
Anti-Inflammatory Agents, Non-Steroidal
Storage : Store at -20°C under inert atmosphere
Synonyms :
Leflunomide Impurity B; A77 1726; A771726; A77-1726; HMR1726; HMR-1726; HMR 1726; N-(4-Trifluoromethylphenyl)-2-cyano-3-hydroxycrotonamide; 2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-2-beuteamide; LEF-M; Leflunomide EP Impurity B; Aubagio; (2Z)-2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-2-butenamide; Femorix

More details are to be found here

Purity : 98%
Smile code : C/C(O)=C(C#N)/C(NC1=CC=C(C(F)(F)F)C=C1)=O
MDL Number : MFCD00910058
MolFormula : C12H9F3N2O2
MolWeight : 270.2073
Available in stock : 82.356