BGC > Product Search > Doxorubicin hydrochloride

Appearance	Orange-red or red crystalline powder; No visible evidence of contamination by foreign matter.
Solubility	Soluble in water and methanol; slightly soluble in ethanol; practically insoluble in acetone.
Identification A	IR spectrum corresponds to the IR spectrum of the reference standard.
Identification B	The retention time of the doxorubicin peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation, as obtained in the Assay.
PH	4.0 to 5.5
Water	≤ 4.0%
Residual solvents
Acetone	≤ 0.5％
Acetone+Ethanol	≤ 2.5％
Methanol	≤ 0.3％
Dichloromethane	≤ 0.06％
Related substances
Impurity A(Doxorubicinone)	≤ 0.5％
Any other unknown Impurity	≤ 0.2％
Total unknown impurities	≤ 0.5％
Total impurities	≤ 1.0％
Assay	98.0％ to 102.0％ of C27H29NO11•HCLCalculated on the anhydrous, solvent-free basis

Appearance	Orange-red or red crystalline powder; No visible evidence of contamination by foreign matter.
Solubility	Soluble in water and methanol; slightly soluble in ethanol; practically insoluble in acetone.
Identification A	IR spectrum corresponds to the IR spectrum of the reference standard.
Identification B	The retention time of the doxorubicin peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation, as obtained in the Assay.
PH	4.0 to 5.5
Water	≤ 4.0%
Residual solvents
Acetone	≤ 0.5％
Acetone+Ethanol	≤ 2.5％
Methanol	≤ 0.3％
Dichloromethane	≤ 0.06％
Related substances
Impurity A(Doxorubicinone)	≤ 0.5％
Any other unknown Impurity	≤ 0.2％
Total unknown impurities	≤ 0.5％
Total impurities	≤ 1.0％
Assay	98.0％ to 102.0％ of C27H29NO11•HCLCalculated on the anhydrous, solvent-free basis

Appearance	Orange-red or red crystalline powder; No visible evidence of contamination by foreign matter.
Solubility	Soluble in water and methanol; slightly soluble in ethanol; practically insoluble in acetone.
Identification A	IR spectrum corresponds to the IR spectrum of the reference standard.
Identification B	The retention time of the doxorubicin peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation, as obtained in the Assay.
PH	4.0 to 5.5
Water	≤ 4.0%
Residual solvents
Acetone	≤ 0.5％
Acetone+Ethanol	≤ 2.5％
Methanol	≤ 0.3％
Dichloromethane	≤ 0.06％
Related substances
Impurity A(Doxorubicinone)	≤ 0.5％
Any other unknown Impurity	≤ 0.2％
Total unknown impurities	≤ 0.5％
Total impurities	≤ 1.0％
Assay	98.0％ to 102.0％ of C27H29NO11•HCLCalculated on the anhydrous, solvent-free basis

Molecular Formula: C27H29NO11.HCl
Molecular Weight: 579,99

Molecular Formula: C27H29NO11.HCl
Molecular Weight: 579,99

Molecular Formula: C27H29NO11.HCl
Molecular Weight: 579,99

Molecular Formula: C27H29NO11.HCl
Molecular Weight: 579,99

Molecular Formula: C27H29NO11.HCl
Molecular Weight: 579,99

Molecular Formula: C27H29NO11.HCl
Molecular Weight: 579,99

Molecular Formula: C27H29NO11.HCl
Molecular Weight: 579,99

Molecular Formula: C27H29NO11.HCl
Molecular Weight: 579,99

Description :
Doxorubicin is an anthracycline antibiotic with antineoplastic activity produced by the bacterium Streptomyces peucetius var. Doxorubicin is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis.

• Molecular Weight :579.98
• Boiling Point :810.3°C at 760 mmHg
• Melting Point :> 168°C
• Purity :> 98%

Molecular Formula :
C27H30ClNO11
Canonical SMILES :
CC1C(C(CC(O1)OC2CC(CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)O.Cl
InChI :
InChI=1S/C27H29NO11.ClH/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34;/h3-5,10,13,15,17,22,29,31,33,35-36H,6-9,28H2,1-2H3;1H/t10-,13-,15-,17-,22+,27-;/m0./s1
InChIKey :
MWWSFMDVAYGXBV-RUELKSSGSA-N
Solubility :
Soluble ethanol, methanol, DMF, DMSO
Appearance :
Orange Crystal Powder
Application :
ADCs Cytotoxin
Storage : Store at -20°C
Synonyms :
Doxorubicin HCl

More details are to be found here

Description :
Doxorubicin is an anthracycline antibiotic with antineoplastic activity produced by the bacterium Streptomyces peucetius var. Doxorubicin is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis.

• Molecular Weight :579.98
• Boiling Point :810.3°C at 760 mmHg
• Melting Point :> 168°C
• Purity :> 98%

Molecular Formula :
C27H30ClNO11
Canonical SMILES :
CC1C(C(CC(O1)OC2CC(CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)O.Cl
InChI :
InChI=1S/C27H29NO11.ClH/c1-10-22(31)13(28)6-17(38-10)39-15-8-27(36,16(30)9-29)7-12-19(15)26(35)21-20(24(12)33)23(32)11-4-3-5-14(37-2)18(11)25(21)34;/h3-5,10,13,15,17,22,29,31,33,35-36H,6-9,28H2,1-2H3;1H/t10-,13-,15-,17-,22+,27-;/m0./s1
InChIKey :
MWWSFMDVAYGXBV-RUELKSSGSA-N
Solubility :
Soluble ethanol, methanol, DMF, DMSO
Appearance :
Orange Crystal Powder
Application :
ADCs Cytotoxin
Storage : Store at -20°C
Synonyms :
Doxorubicin HCl

More details are to be found here

Purity : 99+%
Smile code : COC1=CC=CC2=C1C(C3=C(C(O)=C4C[C@](O)(C[C@@H](C4=C3O)O[C@H]5C[C@@H]([C@@H]([C@@H](O5)C)O)N)C(CO)=O)C2=O)=O.[H]Cl
MDL Number : MFCD00077757
MolFormula : C27H30ClNO11
MolWeight : 579.9802
Available in stock : 233.841

More details are to be found here

Purity : 99+%
Smile code : COC1=CC=CC2=C1C(C3=C(C(O)=C4C[C@](O)(C[C@@H](C4=C3O)O[C@H]5C[C@@H]([C@@H]([C@@H](O5)C)O)N)C(CO)=O)C2=O)=O.[H]Cl
MDL Number : MFCD00077757
MolFormula : C27H30ClNO11
MolWeight : 579.9802
Available in stock : 233.841

More details are to be found here

Purity : 99+%
Smile code : COC1=CC=CC2=C1C(C3=C(C(O)=C4C[C@](O)(C[C@@H](C4=C3O)O[C@H]5C[C@@H]([C@@H]([C@@H](O5)C)O)N)C(CO)=O)C2=O)=O.[H]Cl
MDL Number : MFCD00077757
MolFormula : C27H30ClNO11
MolWeight : 579.9802
Available in stock : 233.841

More details are to be found here

Purity : 99+%
Smile code : COC1=CC=CC2=C1C(C3=C(C(O)=C4C[C@](O)(C[C@@H](C4=C3O)O[C@H]5C[C@@H]([C@@H]([C@@H](O5)C)O)N)C(CO)=O)C2=O)=O.[H]Cl
MDL Number : MFCD00077757
MolFormula : C27H30ClNO11
MolWeight : 579.9802
Available in stock : 233.841

More details are to be found here