BGC > Product Search > Naquotinib

Molecular Formula: C30H42N8O3
Molecular Weight: 562.70628

Molecular Formula: C30H42N8O3
Molecular Weight: 562.70628

Description :
Naquotinib is an irreversible, third-generation, mutant-selective, epidermal growth factor receptor (EGFR) inhibitor, with potential antineoplastic activity with IC50 of 8-33 nM toward EGFR mutants.

• Molecular Weight :562.719
• Purity :≥98%

Molecular Formula :
C30H42N8O3
Canonical SMILES :
CCC1=NC(=C(N=C1OC2CCN(C2)C(=O)C=C)NC3=CC=C(C=C3)N4CCC(CC4)N5CCN(CC5)C)C(=O)N
InChI :
InChI=1S/C30H42N8O3/c1-4-25-30(41-24-12-15-38(20-24)26(39)5-2)34-29(27(33-25)28(31)40)32-21-6-8-22(9-7-21)36-13-10-23(11-14-36)37-18-16-35(3)17-19-37/h5-9,23-24H,2,4,10-20H2,1,3H3,(H2,31,40)(H,32,34)/t24-/m1/s1
InChIKey :
QKDCLUARMDUUKN-XMMPIXPASA-N
Solubility :
Soluble in DMSO.
Appearance :
White Solid
Storage : Store at -20°C
Synonyms :
ASP 8273; ASP8273; ASP-8273; (R)-5-((1-acryloylpyrrolidin-3-yl)oxy)-6-ethyl-3-((4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)amino)pyrazine-2-carboxamide

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