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Suppliers for
Asciminib
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Properties | CAS |
1492952-76-7 |
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2 Registered suppliers
Description : Asciminib, also known as ABL-001, is a potent and selective allosteric Bcr-Abl inhibitor. Asciminib inhibits Ba/F3 cell growth with an IC50 of 0.25 nM. - Molecular Weight :449.843
Molecular Formula : C20H18ClF2N5O3 Canonical SMILES : C1CN(CC1O)C2=NC=C(C=C2C3=CC=NN3)C(=O)NC4=CC=C(C=C4)OC(F)(F)Cl InChI : InChI=1S/C20H18ClF2N5O3/c21-20(22,23)31-15-3-1-13(2-4-15)26-19(30)12-9-16(17-5-7-25-27-17)18(24-10-12)28-8-6-14(29)11-28/h1-5,7,9-10,14,29H,6,8,11H2,(H,25,27)(H,26,30)/t14-/m1/s1 InChIKey : VOVZXURTCKPRDQ-CQSZACIVSA-N Solubility : Soluble in DMSO. Application : Tyrosine Kinase Inhibitors Storage : Store in a cool and dry place (or refer to the Certificate of Analysis). Synonyms : ABL-001; ABL 001; ABL001; N-[4-[chloro(difluoro)methoxy]phenyl]-6-[(3R)-3-hydroxypyrrolidin-1-yl]-5-(1H-pyrazol-5-yl)pyridine-3-carboxamide
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Asciminib
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Last update 2024-05-23
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