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Artesunate



Properties

CAS   88495-63-0 
Formula   C19H28O8 

Structure

23 Registered suppliers


Appearance   White crystalline powder, odorless
Solubility   Free soluble in ethanol, acetone or chloroform,very slightly soluble in water
Specific optical rotation   +4.5º-+6.5º
Identification  
TLC   The principal spot in the chromatogram obtained with the test solution is similar in position, colour to the principal spot in the chromatogram obtained with the reference solution
HPLC   The retention time of main peak of test and standard are concordant
IR   Infrared absorption spectrum of test and standard (or infrared reference spectra No.221) are concordant
Acidity   3.5-4.5
Appearance of solution   Solution S is clear and not more intensely colored than reference solution
Chlorides   Not more pronounced(0.02%)
Related substances(HPLC)  
Dihydroartemisinin   ≤ 1.0%
Artemisinin   ≤ 0.5%
Impurity I   ≤ 0.2%
Any other impurity   ≤ 0.2%
Total impurites   ≤ 2.0%
Water   ≤ 0.5%
Residual on ignition   ≤ 0.1%
Heavy metal   ≤ 20PPM
Bacterial endotoxin   ≤ 1.25EU
Assy(HPLC)   98.0-102.0%


Appearance   White crystalline powder, odorless
Solubility   Free soluble in ethanol, acetone or chloroform,very slightly soluble in water
Specific optical rotation   +4.5º-+6.5º
Identification  
TLC   The principal spot in the chromatogram obtained with the test solution is similar in position, colour to the principal spot in the chromatogram obtained with the reference solution
HPLC   The retention time of main peak of test and standard are concordant
IR   Infrared absorption spectrum of test and standard (or infrared reference spectra No.221) are concordant
Acidity   3.5-4.5
Appearance of solution   Solution S is clear and not more intensely colored than reference solution
Chlorides   Not more pronounced(0.02%)
Related substances(HPLC)  
Dihydroartemisinin   ≤ 1.0%
Artemisinin   ≤ 0.5%
Impurity I   ≤ 0.2%
Any other impurity   ≤ 0.2%
Total impurites   ≤ 2.0%
Water   ≤ 0.5%
Residual on ignition   ≤ 0.1%
Heavy metal   ≤ 20PPM
Bacterial endotoxin   ≤ 1.25EU
Assy(HPLC)   98.0-102.0%


Appearance   White crystalline powder, odorless
Solubility   Free soluble in ethanol, acetone or chloroform,very slightly soluble in water
Specific optical rotation   +4.5º-+6.5º
Identification  
TLC   The principal spot in the chromatogram obtained with the test solution is similar in position, colour to the principal spot in the chromatogram obtained with the reference solution
HPLC   The retention time of main peak of test and standard are concordant
IR   Infrared absorption spectrum of test and standard (or infrared reference spectra No.221) are concordant
Acidity   3.5-4.5
Appearance of solution   Solution S is clear and not more intensely colored than reference solution
Chlorides   Not more pronounced(0.02%)
Related substances(HPLC)  
Dihydroartemisinin   ≤ 1.0%
Artemisinin   ≤ 0.5%
Impurity I   ≤ 0.2%
Any other impurity   ≤ 0.2%
Total impurites   ≤ 2.0%
Water   ≤ 0.5%
Residual on ignition   ≤ 0.1%
Heavy metal   ≤ 20PPM
Bacterial endotoxin   ≤ 1.25EU
Assy(HPLC)   98.0-102.0%


Appearance   White crystalline powder, odorless
Solubility   Free soluble in ethanol, acetone or chloroform,very slightly soluble in water
Specific optical rotation   +4.5º-+6.5º
Identification  
TLC   The principal spot in the chromatogram obtained with the test solution is similar in position, colour to the principal spot in the chromatogram obtained with the reference solution
HPLC   The retention time of main peak of test and standard are concordant
IR   Infrared absorption spectrum of test and standard (or infrared reference spectra No.221) are concordant
Acidity   3.5-4.5
Appearance of solution   Solution S is clear and not more intensely colored than reference solution
Chlorides   Not more pronounced(0.02%)
Related substances(HPLC)  
Dihydroartemisinin   ≤ 1.0%
Artemisinin   ≤ 0.5%
Impurity I   ≤ 0.2%
Any other impurity   ≤ 0.2%
Total impurites   ≤ 2.0%
Water   ≤ 0.5%
Residual on ignition   ≤ 0.1%
Heavy metal   ≤ 20PPM
Bacterial endotoxin   ≤ 1.25EU
Assy(HPLC)   98.0-102.0%


Molecular Formula: C19H28O8
Molecular Weight: 384,42

More details are to be found here
Molecular Formula: C19H28O8
Molecular Weight: 384,42

More details are to be found here
Molecular Formula: C19H28O8
Molecular Weight: 384,42

More details are to be found here
Molecular Formula: C19H28O8
Molecular Weight: 384,42

More details are to be found here
Molecular Formula: C19H28O8
Molecular Weight: 384,42

More details are to be found here
Molecular Formula: C19H28O8
Molecular Weight: 384,42

More details are to be found here
Molecular Formula: C19H28O8
Molecular Weight: 384,42

More details are to be found here
Molecular Formula: C19H28O8
Molecular Weight: 384,42

More details are to be found here
Description :
Artesunate is a derivative of the natural product artemisinin which effectively kills the malarial parasites P. falciparum and P. vivax. It also kills trematodes of the species Schistosoma, providing protection against schistosomiasis.
  • Molecular Weight :384.42
  • Boiling Point :507.1±50.0 °C at 760 mmHg
  • Melting Point :131-135 °C
  • Purity :> 99%
Molecular Formula :
C19H28O8
Canonical SMILES :
CC1CCC2C(C(OC3C24C1CCC(O3)(OO4)C)OC(=O)CCC(=O)O)C
InChI :
InChI=1S/C19H28O8/c1-10-4-5-13-11(2)16(23-15(22)7-6-14(20)21)24-17-19(13)12(10)8-9-18(3,25-17)26-27-19/h10-13,16-17H,4-9H2,1-3H3,(H,20,21)/t10-,11-,12+,13+,16+,17-,18?,19-/m1/s1
InChIKey :
FIHJKUPKCHIPAT-JQXDXKTESA-N
Solubility :
Soluble in DMSO (25 mg/ml), and ethanol (25 mg/ml)
Appearance :
White Powder
Storage : Store at +4 °C, in dark place.
Synonyms :
Succinyl dihydroartemisinin; Dihydroartemisinine-12-alpha-succinate; Artesunate (superseded RN); Artesunate; Armax 200; SM-804; WR-256283; HSDB-7458; SM804; WR256283; HSDB7458; SM 804; WR 256283; HSDB 7458

More details are to be found here
Description :
Artesunate is a derivative of the natural product artemisinin which effectively kills the malarial parasites P. falciparum and P. vivax. It also kills trematodes of the species Schistosoma, providing protection against schistosomiasis.
  • Molecular Weight :384.42
  • Boiling Point :507.1±50.0 °C at 760 mmHg
  • Melting Point :131-135 °C
  • Purity :> 99%
Molecular Formula :
C19H28O8
Canonical SMILES :
CC1CCC2C(C(OC3C24C1CCC(O3)(OO4)C)OC(=O)CCC(=O)O)C
InChI :
InChI=1S/C19H28O8/c1-10-4-5-13-11(2)16(23-15(22)7-6-14(20)21)24-17-19(13)12(10)8-9-18(3,25-17)26-27-19/h10-13,16-17H,4-9H2,1-3H3,(H,20,21)/t10-,11-,12+,13+,16+,17-,18?,19-/m1/s1
InChIKey :
FIHJKUPKCHIPAT-JQXDXKTESA-N
Solubility :
Soluble in DMSO (25 mg/ml), and ethanol (25 mg/ml)
Appearance :
White Powder
Storage : Store at +4 °C, in dark place.
Synonyms :
Succinyl dihydroartemisinin; Dihydroartemisinine-12-alpha-succinate; Artesunate (superseded RN); Artesunate; Armax 200; SM-804; WR-256283; HSDB-7458; SM804; WR256283; HSDB7458; SM 804; WR 256283; HSDB 7458

More details are to be found here
Description :
Artesunate is a derivative of the natural product artemisinin which effectively kills the malarial parasites P. falciparum and P. vivax. It also kills trematodes of the species Schistosoma, providing protection against schistosomiasis.
  • Molecular Weight :384.42
  • Boiling Point :507.1±50.0 °C at 760 mmHg
  • Melting Point :131-135 °C
  • Purity :> 99%
Molecular Formula :
C19H28O8
Canonical SMILES :
CC1CCC2C(C(OC3C24C1CCC(O3)(OO4)C)OC(=O)CCC(=O)O)C
InChI :
InChI=1S/C19H28O8/c1-10-4-5-13-11(2)16(23-15(22)7-6-14(20)21)24-17-19(13)12(10)8-9-18(3,25-17)26-27-19/h10-13,16-17H,4-9H2,1-3H3,(H,20,21)/t10-,11-,12+,13+,16+,17-,18?,19-/m1/s1
InChIKey :
FIHJKUPKCHIPAT-JQXDXKTESA-N
Solubility :
Soluble in DMSO (25 mg/ml), and ethanol (25 mg/ml)
Appearance :
White Powder
Storage : Store at +4 °C, in dark place.
Synonyms :
Succinyl dihydroartemisinin; Dihydroartemisinine-12-alpha-succinate; Artesunate (superseded RN); Artesunate; Armax 200; SM-804; WR-256283; HSDB-7458; SM804; WR256283; HSDB7458; SM 804; WR 256283; HSDB 7458

More details are to be found here
Description :
Artesunate is a derivative of the natural product artemisinin which effectively kills the malarial parasites P. falciparum and P. vivax. It also kills trematodes of the species Schistosoma, providing protection against schistosomiasis.
  • Molecular Weight :384.42
  • Boiling Point :507.1±50.0 °C at 760 mmHg
  • Melting Point :131-135 °C
  • Purity :> 99%
Molecular Formula :
C19H28O8
Canonical SMILES :
CC1CCC2C(C(OC3C24C1CCC(O3)(OO4)C)OC(=O)CCC(=O)O)C
InChI :
InChI=1S/C19H28O8/c1-10-4-5-13-11(2)16(23-15(22)7-6-14(20)21)24-17-19(13)12(10)8-9-18(3,25-17)26-27-19/h10-13,16-17H,4-9H2,1-3H3,(H,20,21)/t10-,11-,12+,13+,16+,17-,18?,19-/m1/s1
InChIKey :
FIHJKUPKCHIPAT-JQXDXKTESA-N
Solubility :
Soluble in DMSO (25 mg/ml), and ethanol (25 mg/ml)
Appearance :
White Powder
Storage : Store at +4 °C, in dark place.
Synonyms :
Succinyl dihydroartemisinin; Dihydroartemisinine-12-alpha-succinate; Artesunate (superseded RN); Artesunate; Armax 200; SM-804; WR-256283; HSDB-7458; SM804; WR256283; HSDB7458; SM 804; WR 256283; HSDB 7458

More details are to be found here
Description :
Artesunate is a derivative of the natural product artemisinin which effectively kills the malarial parasites P. falciparum and P. vivax. It also kills trematodes of the species Schistosoma, providing protection against schistosomiasis.
  • Molecular Weight :384.42
  • Boiling Point :507.1±50.0 °C at 760 mmHg
  • Melting Point :131-135 °C
  • Purity :> 99%
Molecular Formula :
C19H28O8
Canonical SMILES :
CC1CCC2C(C(OC3C24C1CCC(O3)(OO4)C)OC(=O)CCC(=O)O)C
InChI :
InChI=1S/C19H28O8/c1-10-4-5-13-11(2)16(23-15(22)7-6-14(20)21)24-17-19(13)12(10)8-9-18(3,25-17)26-27-19/h10-13,16-17H,4-9H2,1-3H3,(H,20,21)/t10-,11-,12+,13+,16+,17-,18?,19-/m1/s1
InChIKey :
FIHJKUPKCHIPAT-JQXDXKTESA-N
Solubility :
Soluble in DMSO (25 mg/ml), and ethanol (25 mg/ml)
Appearance :
White Powder
Storage : Store at +4 °C, in dark place.
Synonyms :
Succinyl dihydroartemisinin; Dihydroartemisinine-12-alpha-succinate; Artesunate (superseded RN); Artesunate; Armax 200; SM-804; WR-256283; HSDB-7458; SM804; WR256283; HSDB7458; SM 804; WR 256283; HSDB 7458

More details are to be found here
Description :
Artesunate is a derivative of the natural product artemisinin which effectively kills the malarial parasites P. falciparum and P. vivax. It also kills trematodes of the species Schistosoma, providing protection against schistosomiasis.
  • Molecular Weight :384.42
  • Boiling Point :507.1±50.0 °C at 760 mmHg
  • Melting Point :131-135 °C
  • Purity :> 99%
Molecular Formula :
C19H28O8
Canonical SMILES :
CC1CCC2C(C(OC3C24C1CCC(O3)(OO4)C)OC(=O)CCC(=O)O)C
InChI :
InChI=1S/C19H28O8/c1-10-4-5-13-11(2)16(23-15(22)7-6-14(20)21)24-17-19(13)12(10)8-9-18(3,25-17)26-27-19/h10-13,16-17H,4-9H2,1-3H3,(H,20,21)/t10-,11-,12+,13+,16+,17-,18?,19-/m1/s1
InChIKey :
FIHJKUPKCHIPAT-JQXDXKTESA-N
Solubility :
Soluble in DMSO (25 mg/ml), and ethanol (25 mg/ml)
Appearance :
White Powder
Storage : Store at +4 °C, in dark place.
Synonyms :
Succinyl dihydroartemisinin; Dihydroartemisinine-12-alpha-succinate; Artesunate (superseded RN); Artesunate; Armax 200; SM-804; WR-256283; HSDB-7458; SM804; WR256283; HSDB7458; SM 804; WR 256283; HSDB 7458

More details are to be found here

Detailed information on the suppliers of Artesunate

Properties:

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