BGC > Product Search > Irbinitinib

Molecular Formula: C26H24N8O2
Molecular Weight: 480.52116

Molecular Formula: C26H24N8O2
Molecular Weight: 480.52116

Molecular Formula: C26H24N8O2
Molecular Weight: 480.52116

Description :
Irbinitinib,also known as ARRY-380 and ONT-380, is an orally bioavailable inhibitor of the human epidermal growth factor receptor tyrosine kinase ErbB-2 (also called HER2) with potential antineoplastic activity. ErbB-2 is overexpressed in a variety of cancers and plays an important role in cellular proliferation and differentiation.

• Molecular Weight :480.532
• Purity :0.98

Molecular Formula :
C26H24N8O2
Canonical SMILES :
CC1=C(C=CC(=C1)NC2=NC=NC3=C2C=C(C=C3)NC4=NC(CO4)(C)C)OC5=CC6=NC=NN6C=C5
InChI :
InChI=1S/C26H24N8O2/c1-16-10-17(5-7-22(16)36-19-8-9-34-23(12-19)28-15-30-34)31-24-20-11-18(4-6-21(20)27-14-29-24)32-25-33-26(2,3)13-35-25/h4-12,14-15H,13H2,1-3H3,(H,32,33)(H,27,29,31)
InChIKey :
SDEAXTCZPQIFQM-UHFFFAOYSA-N
Appearance :
Solid powder
Application :
Antineoplastic Agents
Synonyms :
ARRY-380; ARRY 380; ARRY380; ONT-380; ONT-380; ONT-380.

More details are to be found here

Description :
Irbinitinib,also known as ARRY-380 and ONT-380, is an orally bioavailable inhibitor of the human epidermal growth factor receptor tyrosine kinase ErbB-2 (also called HER2) with potential antineoplastic activity. ErbB-2 is overexpressed in a variety of cancers and plays an important role in cellular proliferation and differentiation.

• Molecular Weight :480.532
• Purity :0.98

Molecular Formula :
C26H24N8O2
Canonical SMILES :
CC1=C(C=CC(=C1)NC2=NC=NC3=C2C=C(C=C3)NC4=NC(CO4)(C)C)OC5=CC6=NC=NN6C=C5
InChI :
InChI=1S/C26H24N8O2/c1-16-10-17(5-7-22(16)36-19-8-9-34-23(12-19)28-15-30-34)31-24-20-11-18(4-6-21(20)27-14-29-24)32-25-33-26(2,3)13-35-25/h4-12,14-15H,13H2,1-3H3,(H,32,33)(H,27,29,31)
InChIKey :
SDEAXTCZPQIFQM-UHFFFAOYSA-N
Appearance :
Solid powder
Application :
Antineoplastic Agents
Synonyms :
ARRY-380; ARRY 380; ARRY380; ONT-380; ONT-380; ONT-380.

More details are to be found here