BGC > Product Search > Romidepsin

Apparance	white powder
Purity	98% min

Apparance	white powder
Purity	98% min

Apparance	white powder
Purity	98% min

Description :
Romidepsin strongly inhibits HDAC1 and HDAC2 with IC50 of 1.6 nM and 3.9 nM, respectively, but is relatively weak in inhibiting HDAC4 and HDAC6 with IC50 25 nM and 790 nM, respectively.

• Molecular Weight :540.69
• Boiling Point :942.8°C at 760 mmHg
• Melting Point :235-245°C
• Purity :> 98%

Molecular Formula :
C24H36N4O6S2
Canonical SMILES :
CC=C1C(=O)NC(C(=O)OC2CC(=O)NC(C(=O)NC(CSSCCC=C2)C(=O)N1)C(C)C)C(C)C
InChI :
InChI=1S/C24H36N4O6S2/c1-6-16-21(30)28-20(14(4)5)24(33)34-15-9-7-8-10-35-36-12-17(22(31)25-16)26-23(32)19(13(2)3)27-18(29)11-15/h6-7,9,13-15,17,19-20H,8,10-12H2,1-5H3,(H,25,31)(H,26,32)(H,27,29)(H,28,30)/b9-7+,16-6-/t15-,17-,19-,20+/m1/s1
InChIKey :
OHRURASPPZQGQM-GCCNXGTGSA-N
Solubility :
Soluble in Chloroform, DMSO (10 mg/ml at 25°C), Ethanol (<1 mg/ml at 25°C), Methanol, Water (<1 mg/ml at 25°C)
Appearance :
White to Off-white Powder
Application :
For research used only
Storage : Store at -20°C
Synonyms :
Istodax; FK228; FK 228; FK-228; Chromadax; Antibiotic FR 901228; FR901228; FR-901228; NSC-630176; L-Valine, N-((3S,4E)-3-hydroxy-7-mercapto-1-oxo-4-heptenyl)-D-valyl-D-cysteinyl-(2Z)-2-amino-2-butenoxyl-, (4-1)-lactone, cyclic (1-2)-disulfide

More details are to be found here

Purity : 98%
Smile code : C/C=C(NC([C@@H](CSSCC/C=C/[C@@H](O1)CC2=O)NC([C@@H](C(C)C)N2)=O)=O)/C(N[C@@H](C(C)C)C1=O)=O
MDL Number : MFCD18433404
MolFormula : C24H36N4O6S2
MolWeight : 540.6958
Available in stock : 0.14

More details are to be found here