BGC > Product Search > Ixazomib citrate

Molecular Formula: C20H23BCl2N2O9

Molecular Formula: C20H23BCl2N2O9

Description :
The citrate salt form of Ixazomib which is a proteasome inhibitor. It is undergoing a rollover Phase II trial against multiple myeloma, amyloidosis and lymphoma in sorts of countries. IC50 = 3.4 nM.

• Molecular Weight :517.12
• Purity :98%

Molecular Formula :
C20H23BCl2N2O9
Canonical SMILES :
B1(OC(=O)C(O1)(CC(=O)O)CC(=O)O)C(CC(C)C)NC(=O)CNC(=O)C2=C(C=CC(=C2)Cl)Cl
InChI :
InChI=1S/C20H23BCl2N2O9/c1-10(2)5-14(21-33-19(32)20(34-21,7-16(27)28)8-17(29)30)25-15(26)9-24-18(31)12-6-11(22)3-4-13(12)23/h3-4,6,10,14H,5,7-9H2,1-2H3,(H,24,31)(H,25,26)(H,27,28)(H,29,30)/t14-/m0/s1
InChIKey :
MBOMYENWWXQSNW-AWEZNQCLSA-N
Solubility :
Soluble in DMSO (103 mg/mL)
Appearance :
White to Off-white Solid
Storage : Store at -20°C
Synonyms :
4-(carboxymethyl)-2-((R)-1-(2-(2,5-dichlorobenzamido)acetamido)-3-methylbutyl)-6-oxo-1,3,2-dioxaborinane-4-carboxylic acid; MLN9708; MLN-9708; MLN 9708

More details are to be found here