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Suppliers for
Palbociclib
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Properties | CAS |
571190-30-2 | Formula |
C24H29N7O2 |
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14 Registered suppliers
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Molecular Formula: C24H29N7O2 Molecular Weight: 447.54
Description : Palbociclib is an orally available cyclin-dependent kinase (CDK) inhibitor with potential antineoplastic activity. Palbociclib selectively inhibits cyclin-dependent kinase 4 (CDK4) and 6 (CDK6), thereby inhibiting retinoblastoma (Rb) protein phosphorylation early in the G1 phase leading to cell cycle arrest. - Molecular Weight :447.53
- Boiling Point :711.5±70.0°C at 760 mmHg
- Melting Point :> 244°C (dec.)
- Purity :> 95%
Molecular Formula : C24H29N7O2 Canonical SMILES : CC1=C(C(=O)N(C2=NC(=NC=C12)NC3=NC=C(C=C3)N4CCNCC4)C5CCCC5)C(=O)C InChI : InChI=1S/C24H29N7O2/c1-15-19-14-27-24(28-20-8-7-18(13-26-20)30-11-9-25-10-12-30)29-22(19)31(17-5-3-4-6-17)23(33)21(15)16(2)32/h7-8,13-14,17,25H,3-6,9-12H2,1-2H3,(H,26,27,28,29) InChIKey : AHJRHEGDXFFMBM-UHFFFAOYSA-N Solubility : Soluble in Chloroform (Slightly), DMSO (Slightly, Heated), Methanol (Slightly, Heated) Appearance : Pale Yellow to Green Solid Storage : Store at 2-8°C Synonyms : PD 0332991; PD0332991; PD-0332991; Ibrance; 6-Acetyl-8-cyclopentyl-5-methyl-2-[[5-(piperazin-1-yl)pyridin-2-yl]amino]-8H-pyrido[2,3-d]pyrimidin-7-one; 6-Acetyl-8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)pyrido[2,3-d]pyrimidin-7(8H)-one
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Purity : 99% Smile code : O=C1C(C(C)=O)=C(C)C2=CN=C(NC3=NC=C(N4CCNCC4)C=C3)N=C2N1C5CCCC5 MDL Number : MFCD11840850 MolFormula : C24H29N7O2 MolWeight : 447.5328 Available in stock : 347.891
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Properties:
... more properties and specification on Palbociclib
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Last update 2024-06-17
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