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Suppliers for
Lumacaftor
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Properties | CAS |
936727-05-8 | Formula |
C24H18F2N2O5 |
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3 Registered suppliers
Molecular Formula: C24H18F2N2O5 Molecular Weight: 452.4069264
Description : Lumacaftor is the second investigational oral candidate compound for the treatment of cystic fibrosis (CF). Lumacaftor may act to restore the function of the cystic fibrosis transmembrane conductance regulator (CFTR) protein, the defective cell membrane protein responsible for the progression of CF. Lumacaftor defects in the CFTR protein affect the transport of chloride and other ions across cells, and lead to the accumulation of thick, sticky mucus in the lungs of patients with CF. This mucus fosters chronic infection and inflammation, and results in irreversible lung damage. - Molecular Weight :452.41
- Purity :≥98%
Molecular Formula : C24H18F2N2O5 Canonical SMILES : CC1=C(N=C(C=C1)NC(=O)C2(CC2)C3=CC4=C(C=C3)OC(O4)(F)F)C5=CC(=CC=C5)C(=O)O InChI : InChI=1S/C24H18F2N2O5/c1-13-5-8-19(27-20(13)14-3-2-4-15(11-14)21(29)30)28-22(31)23(9-10-23)16-6-7-17-18(12-16)33-24(25,26)32-17/h2-8,11-12H,9-10H2,1H3,(H,29,30)(H,27,28,31) InChIKey : UFSKUSARDNFIRC-UHFFFAOYSA-N Synonyms : VX-809; VX809; VX 809; VRT 826809; VRT826809; VRT-826809
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Purity : 98% Smile code : O=C(O)C1=CC=CC(C2=NC(NC(C3(C4=CC=C(OC(F)(F)O5)C5=C4)CC3)=O)=CC=C2C)=C1 MDL Number : MFCD16659051 MolFormula : C24H18F2N2O5 MolWeight : 452.4069 Available in stock : 241.451
More details are to be found here
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Lumacaftor
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Properties:
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Last update 2024-05-28
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