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BGC > Product Search > Gedunin
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Suppliers for

Gedunin



Properties

CAS   2753-30-2 
Formula   C28H34O7 

Structure

3 Registered suppliers


Description :
Gedunin is a naturally occurring Hsp90 inhibitor. Induces Hsp90-dependent client protein degradation and displays antiproliferative activity in vitro (IC50 values are 3.22, 8.84 and 16.8 μM in SKBr3, MCF-7 and CaCo-2 cancer cell lines respectively). It also exhibits antimalarial activity against P. falciparum (IC50 values are 0.14 and 3.1 μM in parasite development and [3H]-hypoxanthine uptake assays respectively).
  • Molecular Weight :482.57
  • Purity :> 98%
Molecular Formula :
C28H34O7
Canonical SMILES :
CC(=O)OC1CC2C(C(=O)C=CC2(C3C1(C45C(O4)C(=O)OC(C5(CC3)C)C6=COC=C6)C)C)(C)C
InChI :
InChI=1S/C28H34O7/c1-15(29)33-20-13-18-24(2,3)19(30)8-10-25(18,4)17-7-11-26(5)21(16-9-12-32-14-16)34-23(31)22-28(26,35-22)27(17,20)6/h8-10,12,14,17-18,20-22H,7,11,13H2,1-6H3/t17-,18+,20-,21+,22-,25-,26+,27+,28-/m1/s1
InChIKey :
YJXDGWUNRYLINJ-BHAPSIHVSA-N
Solubility :
DMSO: 100 mg/mL; Ethnaol: 10mg/mL with gentle warming
Appearance :
Solid powder
Storage : Store at + 4oC

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Detailed information on the suppliers of Gedunin

Properties:

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