BGC > CAS Search > 955373-67-8

Molecular Formula: C7H6O4S
Molecular Weight: 186.18514

Description :
2,3-Dihydrothieno[3,4-b][1,4]dioxine-2-carboxylic acid, a promising antifungal agent, possesses potent activity against Candidiasis and Aspergillosis. The compound targets 3-ketoacyl-ACP synthase III (FabH), a key enzyme in the biosynthesis of fungal fatty acids, and reduces fungal growth by inducing cellular membrane disruption through inhibition of FabH activity. With its unique mode of action, 2,3-Dihydrothieno[3,4-b][1,4]dioxine-2-carboxylic acid stands as a notably effective potential antifungal therapeutic candidate.

• Molecular Weight :186.181

Molecular Formula :
C7H6O4S
Canonical SMILES :
C1C(OC2=CSC=C2O1)C(=O)O
InChI :
InChI=1S/C7H6O4S/c8-7(9)4-1-10-5-2-12-3-6(5)11-4/h2-4H,1H2,(H,8,9)
InChIKey :
CAHFWFCOAPQXBC-UHFFFAOYSA-N
Synonyms :
2H,3H-Thieno[3,4-B][1,4]dioxine-2-carboxylic acid; EDOT carboxylic acid; Carboxyedot

More details are to be found here

Description :
2,3-Dihydrothieno[3,4-b][1,4]dioxine-2-carboxylic acid, a promising antifungal agent, possesses potent activity against Candidiasis and Aspergillosis. The compound targets 3-ketoacyl-ACP synthase III (FabH), a key enzyme in the biosynthesis of fungal fatty acids, and reduces fungal growth by inducing cellular membrane disruption through inhibition of FabH activity. With its unique mode of action, 2,3-Dihydrothieno[3,4-b][1,4]dioxine-2-carboxylic acid stands as a notably effective potential antifungal therapeutic candidate.

• Molecular Weight :186.181

Molecular Formula :
C7H6O4S
Canonical SMILES :
C1C(OC2=CSC=C2O1)C(=O)O
InChI :
InChI=1S/C7H6O4S/c8-7(9)4-1-10-5-2-12-3-6(5)11-4/h2-4H,1H2,(H,8,9)
InChIKey :
CAHFWFCOAPQXBC-UHFFFAOYSA-N
Synonyms :
2H,3H-Thieno[3,4-B][1,4]dioxine-2-carboxylic acid; EDOT carboxylic acid; Carboxyedot

More details are to be found here

Description :
2,3-Dihydrothieno[3,4-b][1,4]dioxine-2-carboxylic acid, a promising antifungal agent, possesses potent activity against Candidiasis and Aspergillosis. The compound targets 3-ketoacyl-ACP synthase III (FabH), a key enzyme in the biosynthesis of fungal fatty acids, and reduces fungal growth by inducing cellular membrane disruption through inhibition of FabH activity. With its unique mode of action, 2,3-Dihydrothieno[3,4-b][1,4]dioxine-2-carboxylic acid stands as a notably effective potential antifungal therapeutic candidate.

• Molecular Weight :186.181

Molecular Formula :
C7H6O4S
Canonical SMILES :
C1C(OC2=CSC=C2O1)C(=O)O
InChI :
InChI=1S/C7H6O4S/c8-7(9)4-1-10-5-2-12-3-6(5)11-4/h2-4H,1H2,(H,8,9)
InChIKey :
CAHFWFCOAPQXBC-UHFFFAOYSA-N
Synonyms :
2H,3H-Thieno[3,4-B][1,4]dioxine-2-carboxylic acid; EDOT carboxylic acid; Carboxyedot

More details are to be found here