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Suppliers for CAS
585543-15-3
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Properties | CAS |
585543-15-3 | Formula |
C22H26FN3O2 |
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3 Registered suppliers
Leap Chem Co., Ltd
P.R.China
Molecular Formula: C22H26FN3O2 Molecular Weight: 383.46
Aea.ltd
P.R.China
Molecular Formula: C22H26FN3O2 Molecular Weight: 383.46
Molecular Formula: C22H26FN3O2 Molecular Weight: 383.46
BOC Sciences
USA
Description : Losmapimod is a promising new agent against cardiovascular diseases. This drug works by inhibiting p38 MAP kinases, which play an important role in the development of atherosclerosis and heart failure caused by ischemic conditions. Losmapimod did not cause an improvement in exercise tolerance or lung function, despite being well-tolerated in this COPD population. The p38 MAPK inhibitor losmapimod (GW856553) attenuates the pro-inflammatory response in humans by reducing PIC production. - Molecular Weight :383.467
- Purity :98%
Molecular Formula : C22H26FN3O2 Canonical SMILES : CC1=C(C=C(C=C1C2=NC=C(C=C2)C(=O)NCC(C)(C)C)C(=O)NC3CC3)F InChI : InChI=1S/C22H26FN3O2/c1-13-17(9-15(10-18(13)23)21(28)26-16-6-7-16)19-8-5-14(11-24-19)20(27)25-12-22(2,3)4/h5,8-11,16H,6-7,12H2,1-4H3,(H,25,27)(H,26,28) InChIKey : KKYABQBFGDZVNQ-UHFFFAOYSA-N Appearance : White Solid Powder Synonyms : Losmapimod; GW856553; GW-856553; GW 856553 GSK-AHAB; GW856553X; 6-[5-(cyclopropylcarbamoyl)-3-fluoro-2-methylphenyl]-N-(2,2-dimethylpropyl)pyridine-3-carboxamide
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Last update 2024-05-17
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