BGC > CAS Search > 348086-71-5

Molecular Formula: C18H18N4O3S2
Molecular Weight: 402.49052

Molecular Formula: C18H18N4O3S2
Molecular Weight: 402.49052

Description :
BAY 57-1293 represents a new class of potent inhibitors of herpes simplex virus (HSV) that target the virus helicase primase complex. Potent helicase-primase inhibitor (HPI) effective against herpes simplex virus (HSV) infections with IC50 value of 20 nM for inhibition of the replication of both HSV-1 and HSV-2 in Vero cells, and ED50 value of 0.5 mg/kg for both HSV-1 and HSV-2 in the murine lethal challenge model of disseminated herpes.

• Molecular Weight :402.49
• Boiling Point :639.4±65.0 °C at 760 mmHg
• Purity :98%

Molecular Formula :
C18H18N4O3S2
Canonical SMILES :
CC1=C(SC(=N1)N(C)C(=O)CC2=CC=C(C=C2)C3=CC=CC=N3)S(=O)(=O)N
InChI :
InChI=1S/C18H18N4O3S2/c1-12-17(27(19,24)25)26-18(21-12)22(2)16(23)11-13-6-8-14(9-7-13)15-5-3-4-10-20-15/h3-10H,11H2,1-2H3,(H2,19,24,25)
InChIKey :
IVZKZONQVYTCKC-UHFFFAOYSA-N
Solubility :
In vitro: 10 mM in DMSO
Appearance :
White powder
Application :
For research used only
Storage : Powder: -20°C: 3 years 4°C: 2 years In solvent: -80°C: 6 months -20°C: 1 month
Synonyms :
Pritelivir; BAY-57-1293; BAY 57-1293; BAY-57 1293; BAY 57 1293; BAY571293; AIC316; AIC 316; AIC-316

More details are to be found here

Purity : 95%
Smile code : O=C(N(C1=NC(C)=C(S(=O)(N)=O)S1)C)CC2=CC=C(C3=NC=CC=C3)C=C2
MDL Number : MFCD28347970
MolFormula : C18H18N4O3S2
MolWeight : 402.4905
Available in stock : 0.341

More details are to be found here

Smile code:
O=C(N(C1=NC(C)=C(S(=O)(N)=O)S1)C)CC2=CC=C(C3=NC=CC=C3)C=C2
MDL Number:
MFCD28347970
Purity :
95%
Available in stock:
10.284 g

More details are to be found here