Melting Point: 110-115 ° C (lit.)
Density 0.877 g / mL at 20 ° C (lit.)
Refractive index n20 / D 1.461
Storage conditions -20 ° C
Solubility
Sensitivity
BRN 5764110
Stable, but sensitive to moisture. Incompatible with strong acids, strong oxidizing agents, moisture.
CAS database 25952-53-8 (CAS DataBase Reference)
Chemical properties: white crystals. Melting point 111-113 ° C.
Use Protein and nucleic acid crosslinking reagents, can achieve rapid peptide condensation reaction of water-soluble carbodiimide-type condensation agent. EDC (or EDAC) molecular linear structure for the carboxyl and primary amine condensation reaction, and has been widely used.
Uses: It is a water-soluble carbodiimide used as peptide condensing agent and crosslinking agent. It is mainly used as dehydrating agent in peptide, protein, nucleotide synthesis, water-soluble carbodiimide which can realize fast peptide condensation reaction Type condensing agent.
Use of water-soluble enrichment reagents; General carbonyl activation reagent for amide and secondary amine in the process of bonding; with phosphate groups; for peptide synthesis; Protein and nucleic acid cross-linked; Preparation, such as immune cross- Under normal conditions, pH 4.0-6.0 and no buffer, under special conditions, must avoid the use of amines and carboxylate buffer; water-soluble peptide coupling agent; for carbonyl modification in the protein; for ester synthesis