BGC > Product Search > 4,4'-Diaminodiphenyl sulfone

An antibacterial used in the treatment of dermatitis herpetiformis.
Appearance & Physical State	white crystalline powder
Density	1.361 g/cm3
Melting Point	173-178ºC
Boiling Point	511.7ºC at 760 mmHg
Flash Point	263.2ºC
Stability	Stable. Combustible. Incompatible with strong oxidizing agents.
Storage Condition	-20ºC Freezer

An antibacterial used in the treatment of dermatitis herpetiformis.
Appearance & Physical State	white crystalline powder
Density	1.361 g/cm3
Melting Point	173-178ºC
Boiling Point	511.7ºC at 760 mmHg
Flash Point	263.2ºC
Stability	Stable. Combustible. Incompatible with strong oxidizing agents.
Storage Condition	-20ºC Freezer

Appearance	white crystal powder
Assay	99.5% min.
Melting point	175.0 ° C-181.0 ° C
Loss on drying	0.2% max
Packing	25 kg / drum.

Appearance	white crystal powder
Assay	99.5% min.
Melting point	175.0 ° C-181.0 ° C
Loss on drying	0.2% max
Packing	25 kg / drum.

Appearance	white crystal powder
Assay	99.5% min.
Melting point	175.0 ° C-181.0 ° C
Loss on drying	0.2% max
Packing	25 kg / drum.

Molecular Formula: C12H12N2O2S
Molecular Weight: 248.3
Hazard Symbols: Xn
UN Number: 3249
WGKGermany: 1
PackingGroup: III
HS Code: 29051620

Molecular Formula: C12H12N2O2S
Molecular Weight: 248.3
Hazard Symbols: Xn
UN Number: 3249
WGKGermany: 1
PackingGroup: III
HS Code: 29051620

Molecular Formula: C12H12N2O2S
Molecular Weight: 248.3
Hazard Symbols: Xn
UN Number: 3249
WGKGermany: 1
PackingGroup: III
HS Code: 29051620

Molecular Formula: C12H12N2O2S
Molecular Weight: 248.3
Hazard Symbols: Xn
UN Number: 3249
WGKGermany: 1
PackingGroup: III
HS Code: 29051620

Molecular Formula: C12H12N2O2S
Molecular Weight: 248.3
Hazard Symbols: Xn
UN Number: 3249
WGKGermany: 1
PackingGroup: III
HS Code: 29051620

Molecular Formula: C12H12N2O2S
Molecular Weight: 248.3
Hazard Symbols: Xn
UN Number: 3249
WGKGermany: 1
PackingGroup: III
HS Code: 29051620

EINECS :201-248-4
Molecular formula :C12H12N2O2S

EINECS :201-248-4
Molecular formula :C12H12N2O2S

EINECS :201-248-4
Molecular formula :C12H12N2O2S

EINECS :201-248-4
Molecular formula :C12H12N2O2S

EINECS :201-248-4
Molecular formula :C12H12N2O2S

EINECS :201-248-4
Molecular formula :C12H12N2O2S

EINECS :201-248-4
Molecular formula :C12H12N2O2S

EINECS :201-248-4
Molecular formula :C12H12N2O2S

Appearance	White to beige crystalline Powder
Purity, %	≥ 99.00
Water, %	≤ 0.1%

Description :
Dapsone is a sulfone active against a wide range of bacteria but mainly employed for its actions against mycobacterium leprae, which has anti-inflammatory and immunomodulatory effects. It is an antibacterial most commonly used in combination with rifampicin and clofazimine as multidrug therapy (MDT) for the treatment of Mycobacterium leprae infections (leprosy). It antagonized all of the I/R end points measured, showing a remarkable ability to decrease markers of damage through antioxidant, antiinflammatory, and anti-apoptotic effects. It also inhibits bacterial synthesis of dihydrofolic acid, via competition with para-aminobenzoate for the active site of dihydropteroate synthetase.

• Molecular Weight :248.30
• Boiling Point :511.7 ℃ at 760 mmHg
• Melting Point :175.5 ℃
• Purity :> 98 %

Molecular Formula :
C12H12N2O2S
Canonical SMILES :
C1=CC(=CC=C1N)S(=O)(=O)C2=CC=C(C=C2)N
InChI :
InChI=1S/C12H12N2O2S/c13-9-1-5-11(6-2-9)17(15,16)12-7-3-10(14)4-8-12/h1-8H,13-14H2
InChIKey :
MQJKPEGWNLWLTK-UHFFFAOYSA-N
Solubility :
> 37.2 ug/mL
Appearance :
White crystalline powder
Application :
anti-inflammatory agent
Storage : -20ºC Freezer
Synonyms :
4-(4-aminophenyl)sulfonylaniline

More details are to be found here

Description :
Dapsone is a sulfone active against a wide range of bacteria but mainly employed for its actions against mycobacterium leprae, which has anti-inflammatory and immunomodulatory effects. It is an antibacterial most commonly used in combination with rifampicin and clofazimine as multidrug therapy (MDT) for the treatment of Mycobacterium leprae infections (leprosy). It antagonized all of the I/R end points measured, showing a remarkable ability to decrease markers of damage through antioxidant, antiinflammatory, and anti-apoptotic effects. It also inhibits bacterial synthesis of dihydrofolic acid, via competition with para-aminobenzoate for the active site of dihydropteroate synthetase.

• Molecular Weight :248.30
• Boiling Point :511.7 ℃ at 760 mmHg
• Melting Point :175.5 ℃
• Purity :> 98 %

Molecular Formula :
C12H12N2O2S
Canonical SMILES :
C1=CC(=CC=C1N)S(=O)(=O)C2=CC=C(C=C2)N
InChI :
InChI=1S/C12H12N2O2S/c13-9-1-5-11(6-2-9)17(15,16)12-7-3-10(14)4-8-12/h1-8H,13-14H2
InChIKey :
MQJKPEGWNLWLTK-UHFFFAOYSA-N
Solubility :
> 37.2 ug/mL
Appearance :
White crystalline powder
Application :
anti-inflammatory agent
Storage : -20ºC Freezer
Synonyms :
4-(4-aminophenyl)sulfonylaniline

More details are to be found here

Description :
Dapsone is a sulfone active against a wide range of bacteria but mainly employed for its actions against mycobacterium leprae, which has anti-inflammatory and immunomodulatory effects. It is an antibacterial most commonly used in combination with rifampicin and clofazimine as multidrug therapy (MDT) for the treatment of Mycobacterium leprae infections (leprosy). It antagonized all of the I/R end points measured, showing a remarkable ability to decrease markers of damage through antioxidant, antiinflammatory, and anti-apoptotic effects. It also inhibits bacterial synthesis of dihydrofolic acid, via competition with para-aminobenzoate for the active site of dihydropteroate synthetase.

• Molecular Weight :248.30
• Boiling Point :511.7 ℃ at 760 mmHg
• Melting Point :175.5 ℃
• Purity :> 98 %

Molecular Formula :
C12H12N2O2S
Canonical SMILES :
C1=CC(=CC=C1N)S(=O)(=O)C2=CC=C(C=C2)N
InChI :
InChI=1S/C12H12N2O2S/c13-9-1-5-11(6-2-9)17(15,16)12-7-3-10(14)4-8-12/h1-8H,13-14H2
InChIKey :
MQJKPEGWNLWLTK-UHFFFAOYSA-N
Solubility :
> 37.2 ug/mL
Appearance :
White crystalline powder
Application :
anti-inflammatory agent
Storage : -20ºC Freezer
Synonyms :
4-(4-aminophenyl)sulfonylaniline

More details are to be found here

Description :
Dapsone is a sulfone active against a wide range of bacteria but mainly employed for its actions against mycobacterium leprae, which has anti-inflammatory and immunomodulatory effects. It is an antibacterial most commonly used in combination with rifampicin and clofazimine as multidrug therapy (MDT) for the treatment of Mycobacterium leprae infections (leprosy). It antagonized all of the I/R end points measured, showing a remarkable ability to decrease markers of damage through antioxidant, antiinflammatory, and anti-apoptotic effects. It also inhibits bacterial synthesis of dihydrofolic acid, via competition with para-aminobenzoate for the active site of dihydropteroate synthetase.

• Molecular Weight :248.30
• Boiling Point :511.7 ℃ at 760 mmHg
• Melting Point :175.5 ℃
• Purity :> 98 %

Molecular Formula :
C12H12N2O2S
Canonical SMILES :
C1=CC(=CC=C1N)S(=O)(=O)C2=CC=C(C=C2)N
InChI :
InChI=1S/C12H12N2O2S/c13-9-1-5-11(6-2-9)17(15,16)12-7-3-10(14)4-8-12/h1-8H,13-14H2
InChIKey :
MQJKPEGWNLWLTK-UHFFFAOYSA-N
Solubility :
> 37.2 ug/mL
Appearance :
White crystalline powder
Application :
anti-inflammatory agent
Storage : -20ºC Freezer
Synonyms :
4-(4-aminophenyl)sulfonylaniline

More details are to be found here

  Physical State: Solid (Powder)
Solubility: soluble in methyl alcohol, ethyl alcohol, acetone and dilute hydrochloride acid, not dissolve in water

Quality Index:
  Appearance: White Crystalline Powder
Content: 99.5% min.
Melting Point: 175.0°C—181.0°C
Loss on Drying: 0.2% max.(enterprise standard)

Packaging:
  25kg net weight fibre drum
Usage:
  1. for polysulfone amide and other polymers
2. as epoxy hardener
3. as adhesives
4. as gas chromatography
5. for anti-leprosy drug
The above usages mainly involve in aerospace industry, laminates industry, insulated materials, weaving machines and pharmaceutical industry.
Handling and Storage::
  Wash thoroughly after handling. Remove contaminated clothing and wash it before reuse. Avoid contact with eyes, skin and clothing. Avoid ingestion and inhalation. Store in a cool and dry place. Keep the container closed when not in use.

  Physical State: Solid (Powder)
Solubility: soluble in methyl alcohol, ethyl alcohol, acetone and dilute hydrochloride acid, not dissolve in water

Quality Index:
  Appearance: White Crystalline Powder
Content: 99.5% min.
Melting Point: 175.0°C—181.0°C
Loss on Drying: 0.2% max.(enterprise standard)

Packaging:
  25kg net weight fibre drum
Usage:
  1. for polysulfone amide and other polymers
2. as epoxy hardener
3. as adhesives
4. as gas chromatography
5. for anti-leprosy drug
The above usages mainly involve in aerospace industry, laminates industry, insulated materials, weaving machines and pharmaceutical industry.
Handling and Storage::
  Wash thoroughly after handling. Remove contaminated clothing and wash it before reuse. Avoid contact with eyes, skin and clothing. Avoid ingestion and inhalation. Store in a cool and dry place. Keep the container closed when not in use.

  Physical State: Solid (Powder)
Solubility: soluble in methyl alcohol, ethyl alcohol, acetone and dilute hydrochloride acid, not dissolve in water

Quality Index:
  Appearance: White Crystalline Powder
Content: 99.5% min.
Melting Point: 175.0°C—181.0°C
Loss on Drying: 0.2% max.(enterprise standard)

Packaging:
  25kg net weight fibre drum
Usage:
  1. for polysulfone amide and other polymers
2. as epoxy hardener
3. as adhesives
4. as gas chromatography
5. for anti-leprosy drug
The above usages mainly involve in aerospace industry, laminates industry, insulated materials, weaving machines and pharmaceutical industry.
Handling and Storage::
  Wash thoroughly after handling. Remove contaminated clothing and wash it before reuse. Avoid contact with eyes, skin and clothing. Avoid ingestion and inhalation. Store in a cool and dry place. Keep the container closed when not in use.

  Physical State: Solid (Powder)
Solubility: soluble in methyl alcohol, ethyl alcohol, acetone and dilute hydrochloride acid, not dissolve in water

Quality Index:
  Appearance: White Crystalline Powder
Content: 99.5% min.
Melting Point: 175.0°C—181.0°C
Loss on Drying: 0.2% max.(enterprise standard)

Packaging:
  25kg net weight fibre drum
Usage:
  1. for polysulfone amide and other polymers
2. as epoxy hardener
3. as adhesives
4. as gas chromatography
5. for anti-leprosy drug
The above usages mainly involve in aerospace industry, laminates industry, insulated materials, weaving machines and pharmaceutical industry.
Handling and Storage::
  Wash thoroughly after handling. Remove contaminated clothing and wash it before reuse. Avoid contact with eyes, skin and clothing. Avoid ingestion and inhalation. Store in a cool and dry place. Keep the container closed when not in use.