|
|
Suppliers for
Irinotecan ep impurity b
|
Properties | CAS |
19685-09-7 | Formula |
C20H16N2O5 |
|
|
1 Registered suppliers
Description : 10-Hydroxycamptothecin inhibits the growth of BT-20 and MDA-231 cell with IC50 of 34.3 nM and 7.27 nM, respectively, more potently than camptothecin (CPT) with IC50 of > 500 nM. 10-Hydroxycamptothecin is also an impurity of Irinotecan, a Topoisomerase I inhibitor used for the treatment of colon cancer and small cell lung cancer. - Molecular Weight :364.35
- Boiling Point :820.7±65.0°C at 760 mmHg
- Melting Point :268-270°C
- Purity :> 98%
Molecular Formula : C20H16N2O5 Canonical SMILES : CCC1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=CC(=CC5=C4)O)O InChI : InChI=1S/C20H16N2O5/c1-2-20(26)14-7-16-17-11(5-10-6-12(23)3-4-15(10)21-17)8-22(16)18(24)13(14)9-27-19(20)25/h3-7,23,26H,2,8-9H2,1H3/t20-/m0/s1 InChIKey : HAWSQZCWOQZXHI-FQEVSTJZSA-N Solubility : Soluble in Chloroform, DMSO (Slightly), Ethyl acetate, Methanol (Slightly, Heated) Appearance : Light Yellow to Yellow Solid Application : anti-cancer Storage : Store at -20°C Synonyms : 10-Hydroxycamptothecin; Irinotecan Related Compound A; 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4-ethyl-4,9-dihydroxy-, (4S)-; (4S)-4-Ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4-ethyl-4,9-dihydroxy-, (S)-; Camptothecine, 10-hydroxy-; (+)-10-Hydroxycamptothecin; (S)-10-Hydroxycamptothecin; 10-HCPT; 10-Hydroxycamptothecin; 10-Hydroxycamptothecine; Hydroxycamptothecin; NSC 107124; USP Irinotecan Related Compound A; Irinotecan USP Related Compound A
More details are to be found here
|
|
|
Privileged suppliers
Last update 2024-06-18
|