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Suppliers for
Talazoparib
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Properties | CAS |
1207456-01-6 | Formula |
C19H14F2N6O |
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3 Registered suppliers
Description : Talazoparib, also known as BMN-673, is an orally bioavailable inhibitor of the nuclear enzyme poly(ADP-ribose) polymerase (PARP) with potential antineoplastic activity. BMN-673 selectively binds to PARP and prevents PARP-mediated DNA repair of single strand DNA breaks via the base-excision repair pathway. BMN-673 has been proven to be highly active in mouse models of human cancer and also appears to be more selectively cytotoxic with a longer half-life and better bioavailability as compared to other compounds in development. - Molecular Weight :380.359
- Purity :98%
Molecular Formula : C19H14F2N6O Canonical SMILES : CN1C(=NC=N1)C2C(N=C3C=C(C=C4C3=C2NNC4=O)F)C5=CC=C(C=C5)F InChI : InChI=1S/C19H14F2N6O/c1-27-18(22-8-23-27)15-16(9-2-4-10(20)5-3-9)24-13-7-11(21)6-12-14(13)17(15)25-26-19(12)28/h2-8,15-16,25H,1H3,(H,26,28)/t15-,16-/m1/s1 InChIKey : IUEWAGVJRJORLA-HZPDHXFCSA-N Appearance : white solid powder Application : For research used only Synonyms : BMN-673; LT-673. BMN 673; LT 673. BMN673; LT673.
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Properties:
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Last update 2024-06-21
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