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Suppliers for
PD0325901
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Properties | | CAS |
391210-10-9 | | Formula |
C16H14F3IN2O4 |
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5 Registered suppliers
Description : PD-0325901 is a potent bioavailable and selective MEK inhibitor, which targets mitogen-activated protein kinase kinase (MAPK/ERK kinase or MEK) with potential antineoplastic activity. MEK inhibitor PD325901, a derivative of MEK inhibitor CI-1040, selectively binds to and inhibits MEK, which may result in the inhibition of the phosphorylation and activation of MAPK/ERK and the inhibition of tumor cell proliferation. The dual specific threonine/tyrosine kinase MEK is a key component of the RAS/RAF/MEK/ERK signaling pathway that is frequently activated in human tumors. - Molecular Weight :482.198
- Purity :> 98%
Molecular Formula : C16H14F3IN2O4 Canonical SMILES : C1=CC(=C(C=C1I)F)NC2=C(C=CC(=C2F)F)C(=O)NOCC(CO)O InChI : InChI=1S/C16H14F3IN2O4/c17-11-3-2-10(16(25)22-26-7-9(24)6-23)15(14(11)19)21-13-4-1-8(20)5-12(13)18/h1-5,9,21,23-24H,6-7H2,(H,22,25)/t9-/m1/s1
InChIKey :
SUDAHWBOROXANE-SECBINFHSA-N
Appearance :
Solid powder
Application :
Reprogramming, Self-Renewal
Synonyms :
PD 0325901; PD 325901.
More details are to be found here
Description : PD-0325901 is a potent bioavailable and selective MEK inhibitor, which targets mitogen-activated protein kinase kinase (MAPK/ERK kinase or MEK) with potential antineoplastic activity. MEK inhibitor PD325901, a derivative of MEK inhibitor CI-1040, selectively binds to and inhibits MEK, which may result in the inhibition of the phosphorylation and activation of MAPK/ERK and the inhibition of tumor cell proliferation. The dual specific threonine/tyrosine kinase MEK is a key component of the RAS/RAF/MEK/ERK signaling pathway that is frequently activated in human tumors. - Molecular Weight :482.198
- Purity :> 98%
Molecular Formula : C16H14F3IN2O4 Canonical SMILES : C1=CC(=C(C=C1I)F)NC2=C(C=CC(=C2F)F)C(=O)NOCC(CO)O InChI : InChI=1S/C16H14F3IN2O4/c17-11-3-2-10(16(25)22-26-7-9(24)6-23)15(14(11)19)21-13-4-1-8(20)5-12(13)18/h1-5,9,21,23-24H,6-7H2,(H,22,25)/t9-/m1/s1
InChIKey :
SUDAHWBOROXANE-SECBINFHSA-N
Appearance :
Solid powder
Application :
Reprogramming, Self-Renewal
Synonyms :
PD 0325901; PD 325901.
More details are to be found here
Detailed information on the suppliers of
PD0325901 |
Properties:
... more properties and specification on PD0325901
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Last update 2024-06-14
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