BGC > Product Search > Etravirine

Molecular Formula: C20H15BrN6O
Molecular Weight: 435.28

Molecular Formula: C20H15BrN6O
Molecular Weight: 435.28

Molecular Formula: C20H15BrN6O
Molecular Weight: 435.28

Molecular Formula: C20H15BrN6O
Molecular Weight: 435.28

Molecular Formula: C20H15BrN6O
Molecular Weight: 435.28

Description :
Etravirine (ETR, brand name Intelence, formerly known as TMC125) is a drug used for the treatment of HIV. Etravirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI). Etravirine works by reducing the amount of HIV and increasing the number of CD4 or T cells in the blood. Unlike the currently available agents in the class, resistance to other NNRTIs does not seem to confer resistance to etravirine.

• Molecular Weight :435.28
• Boiling Point :637.4±65.0 °C at 760 mmHg
• Melting Point :265 ˚C
• Purity :> 98%

Molecular Formula :
C20H15BrN6O
Canonical SMILES :
CC1=CC(=CC(=C1OC2=NC(=NC(=C2Br)N)NC3=CC=C(C=C3)C#N)C)C#N
InChI :
InChI=1S/C20H15BrN6O/c1-11-7-14(10-23)8-12(2)17(11)28-19-16(21)18(24)26-20(27-19)25-15-5-3-13(9-22)4-6-15/h3-8H,1-2H3,(H3,24,25,26,27)
InChIKey :
PYGWGZALEOIKDF-UHFFFAOYSA-N
Solubility :
In Vitro: DMSO : 50 mg/mL(114.87 mM;Need ultrasonic) In Vivo: 1.Add each solvent one by one:10% DMSO > > 40%PEG300 > > 5%Tween-80 > > 45% saline Solubility: ≥ 2.5 mg/mL (5.74 mM); Clear solution 2.Add each solvent one by one:10% DMSO > > 90%corn oil Solubility: ≥ 2.5 mg/mL (5.74 mM); Clear solution
Appearance :
White to Off-White Solid
Application :
Reverse Transcriptase Inhibitors
Storage : Powder: -20°C: 3 years 4°C: 2 years In solvent: -80°C: 6 months -20°C: 1 month
Synonyms :
R165335; R-165335; R 165335; TMC 125; TMC-125; TMC125; Etravirine. Intelence.

More details are to be found here

Description :
Etravirine (ETR, brand name Intelence, formerly known as TMC125) is a drug used for the treatment of HIV. Etravirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI). Etravirine works by reducing the amount of HIV and increasing the number of CD4 or T cells in the blood. Unlike the currently available agents in the class, resistance to other NNRTIs does not seem to confer resistance to etravirine.

• Molecular Weight :435.28
• Boiling Point :637.4±65.0 °C at 760 mmHg
• Melting Point :265 ˚C
• Purity :> 98%

Molecular Formula :
C20H15BrN6O
Canonical SMILES :
CC1=CC(=CC(=C1OC2=NC(=NC(=C2Br)N)NC3=CC=C(C=C3)C#N)C)C#N
InChI :
InChI=1S/C20H15BrN6O/c1-11-7-14(10-23)8-12(2)17(11)28-19-16(21)18(24)26-20(27-19)25-15-5-3-13(9-22)4-6-15/h3-8H,1-2H3,(H3,24,25,26,27)
InChIKey :
PYGWGZALEOIKDF-UHFFFAOYSA-N
Solubility :
In Vitro: DMSO : 50 mg/mL(114.87 mM;Need ultrasonic) In Vivo: 1.Add each solvent one by one:10% DMSO > > 40%PEG300 > > 5%Tween-80 > > 45% saline Solubility: ≥ 2.5 mg/mL (5.74 mM); Clear solution 2.Add each solvent one by one:10% DMSO > > 90%corn oil Solubility: ≥ 2.5 mg/mL (5.74 mM); Clear solution
Appearance :
White to Off-White Solid
Application :
Reverse Transcriptase Inhibitors
Storage : Powder: -20°C: 3 years 4°C: 2 years In solvent: -80°C: 6 months -20°C: 1 month
Synonyms :
R165335; R-165335; R 165335; TMC 125; TMC-125; TMC125; Etravirine. Intelence.

More details are to be found here

Purity : 98%
Smile code : N#CC1=CC(C)=C(OC2=NC(NC3=CC=C(C#N)C=C3)=NC(N)=C2Br)C(C)=C1
MDL Number : MFCD09837879
MolFormula : C20H15BrN6O
MolWeight : 435.2767
Available in stock : 39.365

More details are to be found here

Purity : 98%
Smile code : N#CC1=CC(C)=C(OC2=NC(NC3=CC=C(C#N)C=C3)=NC(N)=C2Br)C(C)=C1
MDL Number : MFCD09837879
MolFormula : C20H15BrN6O
MolWeight : 435.2767
Available in stock : 39.365

More details are to be found here

Purity : 98%
Smile code : N#CC1=CC(C)=C(OC2=NC(NC3=CC=C(C#N)C=C3)=NC(N)=C2Br)C(C)=C1
MDL Number : MFCD09837879
MolFormula : C20H15BrN6O
MolWeight : 435.2767
Available in stock : 39.365

More details are to be found here