Description :
JK-184 is a potent downstream hedgehog (Hh) signaling antagonist that functions by alcohol dehydrogenase 7 (Adh7) inhibition, preventing Gli-dependent transcriptional activity (IC50 = 30 nM). Hedgehog signaling plays a key role in a wide variety of developmental processes as well as cancer progression. JK-184 exhibits antiproliferative activity.
- Molecular Weight :350.44
- Purity :98%
Molecular Formula :
C19H18N4OS
Appearance :
Light pink color
Application :
Differentiation
Synonyms :
JK184; JK 184
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