BGC > Product Search > Fangchinoline

Description :
Source from vines of Cocculus orbiculatus (L.) DC. Fangchinoline inhibits the production of infectious virions in HIV-1 cDNA transfected 293T cells. It induces G1 arrest in breast cancer cells through cell-cycle regulation.

• Molecular Weight :608.72
• Boiling Point :709.7±60.0 °C at 760 mmHg
• Purity :> 98%

Molecular Formula :
C37H40N2O6
Canonical SMILES :
CN1CCC2=CC(=C3C=C2C1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)CC6C7=C(O3)C(=C(C=C7CCN6C)OC)O)OC)OC
Solubility :
In Vitro: DMSO : 50 mg/mL(82.14 mM;Need ultrasonic) In Vivo: 1.Add each solvent one by one:10% DMSO > > 40%PEG300 > > 5%Tween-80 > > 45% saline Solubility: ≥ 2.08 mg/mL (3.42 mM); Clear solution 2.Add each solvent one by one:10% DMSO > > 90%corn oil Solubility: ≥ 2.08 mg/mL (3.42 mM); Clear solution
Appearance :
Powder
Application :
abirritation and antiinflammation
Storage : 4°C, protect from light * In solvent : -80°C, 6 months -20°C, 1 month (protect from light)
Synonyms :
7-o-demethyltetrandrine; 6,6',12-Trimethoxy-2,2'-Dimethylberbaman-7-ol; (+)-Fangchinoline; Fangchino-line

More details are to be found here

Description :
Source from vines of Cocculus orbiculatus (L.) DC. Fangchinoline inhibits the production of infectious virions in HIV-1 cDNA transfected 293T cells. It induces G1 arrest in breast cancer cells through cell-cycle regulation.

• Molecular Weight :608.72
• Boiling Point :709.7±60.0 °C at 760 mmHg
• Purity :> 98%

Molecular Formula :
C37H40N2O6
Canonical SMILES :
CN1CCC2=CC(=C3C=C2C1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)CC6C7=C(O3)C(=C(C=C7CCN6C)OC)O)OC)OC
Solubility :
In Vitro: DMSO : 50 mg/mL(82.14 mM;Need ultrasonic) In Vivo: 1.Add each solvent one by one:10% DMSO > > 40%PEG300 > > 5%Tween-80 > > 45% saline Solubility: ≥ 2.08 mg/mL (3.42 mM); Clear solution 2.Add each solvent one by one:10% DMSO > > 90%corn oil Solubility: ≥ 2.08 mg/mL (3.42 mM); Clear solution
Appearance :
Powder
Application :
abirritation and antiinflammation
Storage : 4°C, protect from light * In solvent : -80°C, 6 months -20°C, 1 month (protect from light)
Synonyms :
7-o-demethyltetrandrine; 6,6',12-Trimethoxy-2,2'-Dimethylberbaman-7-ol; (+)-Fangchinoline; Fangchino-line

More details are to be found here