BGC > Product Search > Vx-661

Molecular Formula: C26H27F3N2O6
Molecular Weight: 520.4975896

Molecular Formula: C26H27F3N2O6
Molecular Weight: 520.4975896

Description :
VX-661 is a cystic fibrosis transmembrane conductance regulator (CFTR) potentiator used in combination with Ivacaftor in the treatment of cystic fibrosis.

• Molecular Weight :520.50
• Boiling Point :610.8±55.0 °C(Predicted)
• Melting Point :173-177°C
• Purity :98%

Molecular Formula :
C26H27F3N2O6
Canonical SMILES :
CC(C)(CO)C1=CC2=CC(=C(C=C2N1CC(CO)O)F)NC(=O)C3(CC3)C4=CC5=C(C=C4)OC(O5)(F)F
InChI :
InChI=1S/C26H27F3N2O6/c1-24(2,13-33)22-8-14-7-18(17(27)10-19(14)31(22)11-16(34)12-32)30-23(35)25(5-6-25)15-3-4-20-21(9-15)37-26(28,29)36-20/h3-4,7-10,16,32-34H,5-6,11-13H2,1-2H3,(H,30,35)/t16-/m1/s1
InChIKey :
MJUVRTYWUMPBTR-MRXNPFEDSA-N
Solubility :
Soluble in DMSO (Slightly), Methanol (Slightly)
Appearance :
White to Light Yellow Solid
Storage : Store at 2-8°C
Synonyms :
1-(2,2-Difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(2-hydroxy-1,1-dimethylethyl)-1H-indol-5-yl]cyclopropanecarboxamide; VX 661; VX661; Tezacaftor

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