BGC > Product Search > Ebselen

Molecular Formula: C13H9NOSe
Molecular Weight: 274.18
Hazard Symbols: T,N,Xi
UN Number: UN 3283 6.1/PG 3
WGKGermany: 3
PackingGroup: III
HS Code: 29310099

Molecular Formula: C13H9NOSe
Molecular Weight: 274.18
Hazard Symbols: T,N,Xi
UN Number: UN 3283 6.1/PG 3
WGKGermany: 3
PackingGroup: III
HS Code: 29310099

Molecular Formula: C13H9NOSe
Molecular Weight: 274.18
Hazard Symbols: T,N,Xi
UN Number: UN 3283 6.1/PG 3
WGKGermany: 3
PackingGroup: III
HS Code: 29310099

Description :
Ebselen, also known as SPI-1005, is an organoselenium compound with potential anti-oxidant, anti-inflammatory and cytoprotective activity. Upon oral administration of SPI-1005, this agent mimics the activity of glutathione peroxidase (GPx) and can utilize glutathione to reduce other unstable molecules, thus preventing the formation of reactive oxygen species (ROS) and reducing oxidative stress on the cell. In the cochlea, this agent may prevent drug-induced injury to the auditory hair cells thereby preventing hearing loss. GPx is the main antioxidant enzyme in the cochlea and protects the inner ear from loud sounds and biochemical damage. In addition, ebselen is able to inhibit the activity of many enzymes involved in inflammation.

• Molecular Weight :274.192
• Boiling Point :402.8±28.0 °C at 760 mmHg
• Melting Point :178-181 °C
• Purity :> 98%

Molecular Formula :
C13H9NOSe
Canonical SMILES :
C1=CC=C(C=C1)N2C(=O)C3=CC=CC=C3[Se]2
InChI :
InChI=1S/C13H9NOSe/c15-13-11-8-4-5-9-12(11)16-14(13)10-6-2-1-3-7-10/h1-9H
InChIKey :
DYEFUKCXAQOFHX-UHFFFAOYSA-N
Solubility :
In Vitro: DMSO : 50 mg/mL(182.36 mM;Need ultrasonic) In Vivo: 1.Add each solvent one by one:10% DMSO > > 40%PEG300 > > 5%Tween-80 > > 45% saline Solubility: ≥ 2.5 mg/mL (9.12 mM); Clear solution 2.Add each solvent one by one:10% DMSO > > 90%corn oil Solubility: ≥ 2.5 mg/mL (9.12 mM); Clear solution
Appearance :
white solid powder
Storage : Powder: -20°C: 3 years 4°C: 2 years In solvent: -80°C: 6 months -20°C: 1 month
Synonyms :
SPI-1005; SPI1005; SPI 1005; Ebselen; PZ 51; PZ51; PZ-51; DR3305; DR 3305; DR-3305

More details are to be found here

Purity : 98%
Smile code : O=C1N(C2=CC=CC=C2)[Se]C3=CC=CC=C13
MDL Number : MFCD00210937
MolFormula : C13H9NOSe
MolWeight : 274.1767
Available in stock : 30.565

Purity : 98%
Smile code : O=C1N(C2=CC=CC=C2)[Se]C3=CC=CC=C13
MDL Number : MFCD00210937
MolFormula : C13H9NOSe
MolWeight : 274.1767
Available in stock : 30.565

Purity : 98%
Smile code : O=C1N(C2=CC=CC=C2)[Se]C3=CC=CC=C13
MDL Number : MFCD00210937
MolFormula : C13H9NOSe
MolWeight : 274.1767
Available in stock : 30.565