BGC > Product Search > Pf-06651600

Description :
PF-06651600 is a selective JAK3 inhibitor with IC50 value of 0.346 nM. It was shown to inhibit Th1 and Th17 cell differentiation and function in vitro.

• Molecular Weight :285.351
• Purity :> 98%

Molecular Formula :
C15H19N5O
Canonical SMILES :
CC1CCC(CN1C(=O)C=C)NC2=NC=NC3=C2C=CN3
InChI :
InChI=1S/C15H19N5O/c1-3-13(21)20-8-11(5-4-10(20)2)19-15-12-6-7-16-14(12)17-9-18-15/h3,6-7,9-11H,1,4-5,8H2,2H3,(H2,16,17,18,19)/t10-,11+/m0/s1
InChIKey :
CBRJPFGIXUFMTM-WDEREUQCSA-N
Appearance :
White Solid
Synonyms :
Ritlecitinib; PF 06651600; PF06651600; 2-Propen-1-one, 1-[(2S,5R)-2-methyl-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-1-piperidinyl]-

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