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Suppliers for
PF-04418948
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Properties | CAS |
1078166-57-0 |
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4 Registered suppliers
More details are to be found here
Molecular Formula: C22H21F3N6O3S Molecular Weight: 506.5007496 WGKGermany: 3
Molecular Formula: C22H21F3N6O3S Molecular Weight: 506.5007496 WGKGermany: 3
Description : PF-04418948 is a potent and selective prostaglandin EP₂ receptor antagonist with IC50 of 16 nM. Phase 1. PF-04418948 antagonizes the effects of butaprost and PGE2 on an EFS-induced contraction of the human myometrium, and antagonizes PGE2-induced relaxation of carbachol pre-contracted rings of mouse trachea. - Molecular Weight :409.41
- Purity :98%
Molecular Formula : C23H20FNO5 Canonical SMILES : COC1=CC2=C(C=C1)C=C(C=C2)OCC3(CN(C3)C(=O)C4=CC=C(C=C4)F)C(=O)O InChI : InChI=1S/C23H20FNO5/c1-29-19-8-4-17-11-20(9-5-16(17)10-19)30-14-23(22(27)28)12-25(13-23)21(26)15-2-6-18(24)7-3-15/h2-11H,12-14H2,1H3,(H,27,28) InChIKey : LWJGMYMNSNVCEM-UHFFFAOYSA-N Solubility : DMSO: 81mg/mL(197.84mM); Water: <1mg/mL(<1mM); Ethanol: <1mg/mL(<1mM) Appearance : White Solid Storage : 3 years -20℃ powder; 6 months -80℃ in solvent Synonyms : PF04418948; PF-04418948; PF 04418948; PF4418948; PF-4418948; PF 4418948.
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Properties:
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Last update 2024-06-21
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