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Torin 2

BGC Id:714806002874
CAS No:1223001-51-1
Synonyms:Torin 2 ; ; Benzo[h]-1,6-naphthyridin-2(1H)-one, 9-(6-amino-3-pyridinyl)-1-[3-(trifluoromethyl)phenyl]-
Molecular Formula:C24H15F3N4O
Molecular Weight:432.40
EINECS:
Structural Formula

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Description : Torin 2 is a potent and selective mTOR inhibitor with IC50 of 2.1 nM. It inhibits ATM/ATR/DNA-PK with EC50 of 28 nM/35 nM/118 nM, in PC3 cell lines respectively. It is potentially used as an antineoplastic agent.
  • Molecular Weight :432.406
  • Purity :98%
Molecular Formula : C24H15F3N4O Canonical SMILES : C1=CC(=CC(=C1)N2C(=O)C=CC3=CN=C4C=CC(=CC4=C32)C5=CN=C(C=C5)N)C(F)(F)F InChI : 9-(6-Amino-3-pyridinyl)-1-[3-(trifluoromethyl)phenyl]benzo[h]-1,6-naphthyridin-2(1H)-one
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