Afatinib dimaleate

BGC Id:	656384931925
CAS No:	850140-73-7
Synonyms:	2-Butenamide, N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]- 6-quinazolinyl]-4-(dimethylamino)-, (2E)-, (2Z)-2-butenedioate (1:2)
Molecular Formula:	C24H25ClFN5O3.2C4H4O4
Molecular Weight:	491.975
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Description : Afatinib Dimaleate irreversibly inhibits EGFR/HER2 including EGFR(wt), EGFR(L858R), EGFR(L858R/T790M) and HER2 with IC50 of 0.5 nM, 0.4 nM, 10 nM and 14 nM, respectively.

Molecular Weight :717.18
Purity :> 98%

Molecular Formula : C32H33ClFN5O11 Canonical SMILES : CN(C)CC=CC(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)OC4CCOC4.C(=CC(=O)O)C(=O)O.C(=CC(=O)O)C(=O)O InChI :

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