Description :
SC 26196 is a selective Δ6 desaturase inhibitor (IC50 = 0.2 μM in vitro) that displays > 100 fold selectivity over Δ5 and Δ9 desaturases (IC50 > 200 μM in vitro). SC 26196 completely inhibits the conversion of linoleic acid to arachidonic acid (AA). It exhibits anti-inflammatory properties in a mouse edema model.
Molecular Weight :423.55
Purity :≥98% by HPLC
Molecular Formula :
C27H29N5
Canonical SMILES :
α,α-diphenyl-4-[(3-pyridinylmethylene)amino]-1-piperazinepentanenitrile
