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MK 0731

BGC Id:136835250528
CAS No:845256-65-7
Synonyms:mk0731 ; (2s)-4-(2,5-difluorophenyl)-n-[(3r,4s)-3-fluoro-1-methyl-4-piperidinyl]-2,5-dihydro-2-(hydroxymethyl)-n-methyl-2-phenyl-1h-pyrrole-1-carboxamide ; (s)-4-(2,5-difluorophenyl)-n-((3r,4s)-3-fluoro-1-methylpiperidin-4-yl)-2-(hydroxymethyl)-n-methyl-2-phenyl-2,5-dihydro-1h-pyrrole-1-carboxamide ; (r)-2-amino-2-cyclopropyl-1-((s)-4-(2,5-difluorophenyl)-2-phenyl-2h-pyrrol-1(5h)-yl)ethanone ; alr-3456 , mk-0731 ; 1h-pyrrole-1-carboxamide,4-(2,5-difluorophenyl)-n-[(3r,4s)-3-fluoro-1-methyl-4-piperidinyl]-2,5-dihydro-2-(hydroxymethyl)-n-methyl-2-phenyl-,(2s)- ; alr-3456 ; 1h-pyrrole-1-carboxamide, 4-(2,5-difluorophenyl)-n-[(3r,4s)-3-fluoro-1-methyl-4-piperidinyl]-2,5-dihydro-2-(hydroxymethyl)-n-methyl-2-phenyl-, (2s)-
Molecular Formula:C25H28 F3 N3 O2
Molecular Weight:459.509
EINECS:
Structural Formula

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BOC Sciences
Description : MK-0731 is a synthetic small molecule with potential antineoplastic activity. MK0731 selectively inhibits kinesin spindle protein (KSP), which may result in the inhibition of mitotic spindle assembly, induction of cell cycle arrest during the mitotic phase, and apoptosis in tumor cells that overexpress KSP.
  • Molecular Weight :459.513
Molecular Formula : C25H28F3N3O2 Canonical SMILES : CN1CCC(C(C1)F)N(C)C(=O)N2CC(=CC2(CO)C3=CC=CC=C3)C4=C(C=CC(=C4)F >>more

The last intensive check and update was carried out on 2025/03/11.

Identify

Synonyms:
mk0731 ; (2s)-4-(2,5-difluorophenyl)-n-[(3r,4s)-3-fluoro-1-methyl-4-piperidinyl]-2,5-dihydro-2-(hydroxymethyl)-n-methyl-2-phenyl-1h-pyrrole-1-carboxamide ; (s)-4-(2,5-difluorophenyl)-n-((3r,4s)-3-fluoro-1-methylpiperidin-4-yl)-2-(hydroxymethyl)-n-methyl-2-phenyl-2,5-dihydro-1h-pyrrole-1-carboxamide ; (r)-2-amino-2-cyclopropyl-1-((s)-4-(2,5-difluorophenyl)-2-phenyl-2h-pyrrol-1(5h)-yl)ethanone ; alr-3456 , mk-0731 ; 1h-pyrrole-1-carboxamide,4-(2,5-difluorophenyl)-n-[(3r,4s)-3-fluoro-1-methyl-4-piperidinyl]-2,5-dihydro-2-(hydroxymethyl)-n-methyl-2-phenyl-,(2s)- ; alr-3456 ; 1h-pyrrole-1-carboxamide, 4-(2,5-difluorophenyl)-n-[(3r,4s)-3-fluoro-1-methyl-4-piperidinyl]-2,5-dihydro-2-(hydroxymethyl)-n-methyl-2-phenyl-, (2s)-
CAS:
845256-65-7
EINECS:
Molecular Formula:
C25H28 F3 N3 O2
MDL:

Properties

Molecular Weight:
459.509 g·mol−1

Suppliers

BOC Sciences

Unternehmensart: Supplier
BOC Sciences provides a wide range of customer services, bulk and specialty compounds to the pharmaceutical, agrochemical and biotechnology industries. Anemarrhenasaponin-i wird auch durch uns angeboten. We intend to offer you the products and services of the highest quality at the most reasonable, cost efficient prices. Most of our compounds can be supplied ranging from mg to kg and arrive with analytic report. We hope to add immense value to your research projects!
Land: USA   Telefon: +1-631-485-4226   Fax: +1-631-614-7828

BIOZOL Diagnostica Vertrieb GmbH

Unternehmensart: Supplier of chemical products
Land: Germany
Telefon: +49-871-966346-0
Fax: +49-871-966346-13
Chemos®, a subsidiary of BIOZOL Diagnostica Vertrieb GmbH, is a leading supplier of ready to use solutions for the lab and chemical industry. We are producing reagents and standards for the analytical lab and supplying raw materials for the chemical and pharmaceutical industry. BIOZOL Diagnostica Vertrieb GmbH bietet auch 4-Benzyloxypyridine an. The base of our solutions are a portfolio of ~ 200.000 raw materials where ~ 50.000 are already available for R+D ready to order in our shop. We are supplying and producing lab quantities from tiny qua ...

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Leap Chem Co., Ltd
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