KIRA6

BGC Id:	757698981019
CAS No:	1589527-65-0
Synonyms:
Molecular Formula:
Molecular Weight:
EINECS:

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Amadis Chemical Company

BOC Sciences

Description : KIRA6 allosterically inhibits IRE1α RNase kinase activity in vivo and promotes cell survival under ER stress. Systemically, KIRA6 preserves pancreatic β cells, increases insulin, and reduces hyperglycemia in Akita diabetic mice.

Molecular Weight :518.53

Molecular Formula : C28H25F3N6O Canonical SMILES : CC(C)(C)C1=NC(=C2N1C=CN=C2N)C3=CC=C(C4=CC=CC=C43)NC(=O)NC5=CC=CC(=C5)C(F)(F)F InChI : 1-(4-(8-Amino-3-(tert-butyl)imidazo[1,5-a]pyrazin-1-yl)naphthalen-1-yl)-3-(3-(trifluoromethyl)phenyl)urea

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