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Atpenin A5

BGC Id:263293715054
CAS No:119509-24-9
Synonyms:(2s,4s,5r)-1-(2,4-dihydroxy-5,6-dimethoxy-3-pyridinyl)-2,4-dimethyl-5,6-dichloro-1-hexanone ; fo 125a5 ; (2s,4s,5r)-5,6-dichloro-1-(2,4-dihydroxy-5,6-dimethoxypyridin-3-yl)-2,4-dimethyl-1-hexanone ; 2(1h)-pyridinone,3-[(2s,4s,5r)-5,6-dichloro-2,4-dimethyl-1-oxohexyl]-4-hydroxy-5,6-dimethoxy- ; 3-[(2s,4s,5r)-5,6-dichloro-2,4-dimethyl-1-oxohexyl]-4-hydroxy-5,6-dimethoxy-2(1h)-pyridinone ; atpenin a 5 ; 2(1h)-pyridinone,3-(5,6-dichloro-2,4-dimethyl-1-oxohexyl)-4-hydroxy-5,6-dimethoxy-,[2s-(2r*,4r*,5s*)]- ; atpenin a5 ; antibiotic fo 125a5
Molecular Formula:C15H21 Cl2 N O5
Molecular Weight:366.2
EINECS:
Structural Formula

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Description : Atpenin A5 is an inhibitor of SDHB, SDHC and SDHD. It is an antifungal antibiotic produced by Penicillium sp. and an ubiquinone-binding site inhibitor of succinate dehydrogenase with IC50s of 12 nM for nematode and IC50s of 3.7 nM for mammalian mitochondria. Atpenin A5 is the most effective inhibitor against complex II from all the atpenins and has been shown to protect against cardiac-reperfusion injury in rat studies through the stimulation of mitochondrial KATP channels.
  • Molecular Weight :366.2
  • Boiling Point
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Leap Chem
Molecular Formula: C15H21Cl2NO5

The last intensive check and update was carried out on 2025/07/31.

Identify

Synonyms:
(2s,4s,5r)-1-(2,4-dihydroxy-5,6-dimethoxy-3-pyridinyl)-2,4-dimethyl-5,6-dichloro-1-hexanone ; fo 125a5 ; (2s,4s,5r)-5,6-dichloro-1-(2,4-dihydroxy-5,6-dimethoxypyridin-3-yl)-2,4-dimethyl-1-hexanone ; 2(1h)-pyridinone,3-[(2s,4s,5r)-5,6-dichloro-2,4-dimethyl-1-oxohexyl]-4-hydroxy-5,6-dimethoxy- ; 3-[(2s,4s,5r)-5,6-dichloro-2,4-dimethyl-1-oxohexyl]-4-hydroxy-5,6-dimethoxy-2(1h)-pyridinone ; atpenin a 5 ; 2(1h)-pyridinone,3-(5,6-dichloro-2,4-dimethyl-1-oxohexyl)-4-hydroxy-5,6-dimethoxy-,[2s-(2r*,4r*,5s*)]- ; atpenin a5 ; antibiotic fo 125a5
CAS:
119509-24-9
EINECS:
Molecular Formula:
C15H21 Cl2 N O5
MDL:
SMILES:
C/C=C/CBr

Properties

Molecular Weight:
366.2 g·mol−1
Density:
1.31 g/cm3
Melting point:
83-85°C
Boiling point:
532.59° C at 760 mmHg (Predicted)
Solubility:
Soluble in acetone, acetonitrile, chloroform, ethyl acetate, DMSO, methanol, and 100% ethanol. Insoluble in water, and hexane.
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Suppliers

BOC Sciences

Тип компании: Supplier
BOC Sciences provides a wide range of customer services, bulk and specialty compounds to the pharmaceutical, agrochemical and biotechnology industries. We intend to offer you the products and services of the highest quality at the most reasonable, cost efficient prices. Мы поставляем нашу Peptide YY (3-36) (human) химический продукт. Most of our compounds can be supplied ranging from mg to kg and arrive with analytic report. We hope to add immense value to your research projects!
страна: USA   телефон: +1-631-485-4226   факс: +1-631-614-7828

Leap Chem Co., Ltd

Тип компании: Bulk and laboratory supplier
страна: P.R.China
телефон: +852-30606658
LEAPChem, a specialized fine chemicals supplier for research, development and production. LEAPChem provides nearly 50,000 rare and innovative chemical products to support the evolving needs of our customers in research & bulk manufacturing activities. As a highly customer-oriented enterprise, we are committed to providing high-quality customer services and products to our global customers in a cost-effective and efficient manner. Мы продаем DL-3-Phenyllactic acid также. Our client list includes many major pharmac ...

Skyrun Industrial Co., Ltd.

Skyrun Industrial Co.Limited, established in 2003, a state-controlled company (By Skyrun Corp. & High Hope) in China, specializing in developing, producing and handing raw pharmaceutical material and intermediates. We have expanded a compositive entity from initially only as a small manufacturer. We have extensive knowledge of domestic and international pharmaceutical markets. Мы продаем 6-Dodecyne также. Our working range can be start from small amount in research stage to big bulk for industrial produc ...
Тип компании: Leading producer
страна: P.R.China
телефон: +86-576-84015261
факс: +86-576-84015261

BIOZOL Diagnostica Vertrieb GmbH

Тип компании: Supplier of chemical products
Chemos®, a subsidiary of BIOZOL Diagnostica Vertrieb GmbH, is a leading supplier of ready to use solutions for the lab and chemical industry. We are producing reagents and standards for the analytical lab and supplying raw materials for the chemical and pharmaceutical industry. BIOZOL Diagnostica Vertrieb GmbH является продавцом 4-Hydroxymethyl-pyridine-2-carboxylic acid methyl ester. The base of our solutions are a portfolio of ~ 200.000 raw materials where ~ 50.000 are already available for R+D ready to order in our shop. We are supplying and producing lab quantities from tiny qua ...
страна: Germany   телефон: +49-871-966346-0   факс: +49-871-966346-13

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