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Withaferin A

BGC Id:343226575796
CAS No:5119-48-2
Synonyms:(4β,5β,6β,22r)-5,6-epoxy-4,22,27-trihydroxy-1-oxoergosta-2,24-dien-26-oicacidδ-lactone ; withaferin a (7ci) ; 5,6-epoxy-4,27-dihydroxy-1-oxowitha-2,24-dienolide ; 5b-ergosta-2,24-dien-26-oic acid,5,6b-epoxy-4b,22,27-trihydroxy-1-oxo-, d-lactone, (20s,22r)- (8ci) ; ergosta-2,24-dien-26-oicacid, 5,6-epoxy-4,22,27-trihydroxy-1-oxo-, d-lactone, (4b,5b,6b,22r)- ; delta-lactone,(20s,22r)-oxo ; withaferine ; nsc-101088 ; 5,6-beta-epoxy-4-beta,22,27-trihydroxy-1-5-beta-ergosta-24-dien-26-oicacid ; nsc 273757 ; nsc 101088 ; withaferinea ; withaferin a nsc 273757 nsc 101088 ; withaferin a ; withaferine a ; 5,6-epoxy-5h-cyclopenta[a]phenanthrene,ergosta-2,24-dien-26-oic acid deriv.
Molecular Formula:C28H38 O6
Molecular Weight:470.66
EINECS:
Structural Formula

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Description : Withaferin A, also referred to as D004, NSC 101088, used as an important medicinal herb for over 3000 years, is a steroidal lactone derived from Acnistus arborescens, Withania somnifera and other members of Solanaceae family. This natural product has wide range of pharmacological application comprising of anti-obesity, anti-inflammatory, anti-neoplastic, antiangiogenic, etc. It inhibits NF-kB activation and targets vimentin.
  • Molecular Weight :470.60
  • Boiling Point :680.7°C at 760 mmHg
  • Melt
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Molecular Formula: C27H36O7 Molecular Weight: 472.57 Hazard Symbols: T WGKGermany: 3 HS Code: 29322090

The last intensive check and update was carried out on 2025/03/11.

Identify

Synonyms:
(4β,5β,6β,22r)-5,6-epoxy-4,22,27-trihydroxy-1-oxoergosta-2,24-dien-26-oicacidδ-lactone ; withaferin a (7ci) ; 5,6-epoxy-4,27-dihydroxy-1-oxowitha-2,24-dienolide ; 5b-ergosta-2,24-dien-26-oic acid,5,6b-epoxy-4b,22,27-trihydroxy-1-oxo-, d-lactone, (20s,22r)- (8ci) ; ergosta-2,24-dien-26-oicacid, 5,6-epoxy-4,22,27-trihydroxy-1-oxo-, d-lactone, (4b,5b,6b,22r)- ; delta-lactone,(20s,22r)-oxo ; withaferine ; nsc-101088 ; 5,6-beta-epoxy-4-beta,22,27-trihydroxy-1-5-beta-ergosta-24-dien-26-oicacid ; nsc 273757 ; nsc 101088 ; withaferinea ; withaferin a nsc 273757 nsc 101088 ; withaferin a ; withaferine a ; 5,6-epoxy-5h-cyclopenta[a]phenanthrene,ergosta-2,24-dien-26-oic acid deriv.
CAS:
5119-48-2
EINECS:
Molecular Formula:
C28H38 O6
MDL:
MFCD10687098
SMILES:
ClCC1=CC=CC(=C1)C(Cl)=O

Properties

Molecular Weight:
470.66 g·mol−1
Density:
1.28
Melting point:
252-253°C
Boiling point:
680.69° C at 760 mmHg (Predicted)
Solubility:
Soluble in ethanol, and DMSO.
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BOC Sciences

公司類型: Supplier
BOC Sciences provides a wide range of customer services, bulk and specialty compounds to the pharmaceutical, agrochemical and biotechnology industries. BOC Sciences賣家Palbociclib hydrochloride。 We intend to offer you the products and services of the highest quality at the most reasonable, cost efficient prices. Most of our compounds can be supplied ranging from mg to kg and arrive with analytic report. We hope to add immense value to your research projects!
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Hangzhou Lingrui Chemical Co., Ltd.

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國家: P.R.China
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Established in 2010, located in Hangzhou Qinglan science park, lingruichem is a technical company mainly focus on the Custom synthesis, manufacturing, sales of chemicals to various industries. In our R&D centre, we have a staff of skilled and experienced research chemists. 我們賣Dibenzoylmethane的。 This has enabled us to meet the special requirements of our customers and it has enabled us to provide quality products at competitive prices. Lingrui’s credo is committed to your reliable business partne ...

Leap Chem Co., Ltd

LEAPChem, a specialized fine chemicals supplier for research, development and production. LEAPChem provides nearly 50,000 rare and innovative chemical products to support the evolving needs of our customers in research & bulk manufacturing activities. As a highly customer-oriented enterprise, we are committed to providing high-quality customer services and products to our global customers in a cost-effective and efficient manner. Our client list includes many major pharmac ...
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BIOZOL Diagnostica Vertrieb GmbH

公司類型: Supplier of chemical products
Chemos®, a subsidiary of BIOZOL Diagnostica Vertrieb GmbH, is a leading supplier of ready to use solutions for the lab and chemical industry. 我們是賣方Isoformononetin。 We are producing reagents and standards for the analytical lab and supplying raw materials for the chemical and pharmaceutical industry. The base of our solutions are a portfolio of ~ 200.000 raw materials where ~ 50.000 are already available for R+D ready to order in our shop. We are supplying and producing lab quantities from tiny qua ...
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Safety Information

Hazard Classes:
Storage temperature:
Desiccate at -20 °C

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