Description :
WAY-316606 is an inhibitor of the secreted protein sFRP-1, an endogenous antagonist of the secreted glycoprotein Wnt. Modulators of the Wnt pathway have been proposed as anabolic agents for the treatment of osteoporosis or other bone-related disorders. WAY-316606 bound to sFRP-1 with a Kd of 0.08 mM and inhibited it with an EC50 of 0.65 mM.
Molecular Weight :448.475
Purity :> 98%
Molecular Formula :
C18H19F3N2O4S2
Canonical SMILES :
5-(Phenylsulfonyl)-N-(piperidin-4-yl)-2-(trifluoromethyl)benzenesulfonamide
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