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SIS3 hydrochloride

BGC Id:254367198562
CAS No:521984-48-5
Synonyms:sis3 hcl ; sis3 hydrochloride ; (2e)-1-(6,7-dimethoxy-3,4-dihydro-1h-isoquinolin-2-yl)-3-(1-methyl-2-phenyl-1h-pyrrolo[2,3-b]pyridin-3-yl)-propenone hydrochloride ; sis3
Molecular Formula:C28H27N3O3.HCl
Molecular Weight:489.99
EINECS:
Structural Formula

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BOC Sciences
Description : SIS3 is a potent and specific inhibitor of Smad3 via inhibiting the effects of TGF-β1. SIS3 inhibits TGF-β and activin signaling by suppressing Smad3 phosphorylation with no effect on Smad2, p38 MAPK, ERK or PI 3-kinase signaling. It inhibits TGF-β1-induced myofibroblast differentiation of dermal fibroblasts.
  • Molecular Weight :489.99
  • Purity :> 98%
Molecular Formula : C28H27N3O3.HCl Canonical SMILES : CN1 >>more

The last intensive check and update was carried out on 2025/03/11.

Identify

Synonyms:
sis3 hcl ; sis3 hydrochloride ; (2e)-1-(6,7-dimethoxy-3,4-dihydro-1h-isoquinolin-2-yl)-3-(1-methyl-2-phenyl-1h-pyrrolo[2,3-b]pyridin-3-yl)-propenone hydrochloride ; sis3
CAS:
521984-48-5
EINECS:
Molecular Formula:
C28H27N3O3.HCl
MDL:
MFCD09265258
SMILES:
C1=C(C(=NC=C1Br)Br)Cl

Properties

Molecular Weight:
489.99 g·mol−1
Solubility:
Soluble in water: <2 mg/mL: DMSO: >20 mg/mL
download Download Molfile for :
1,2,3,4-Tetrahydro-6,7-dimethoxy-2-[(2E)-3-(1-methyl-2-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-1-oxo-2-propenyl]-isoquinoline Monohydrochloride

Suppliers

Amadis Chemical Company Limited

公司類型: Leading producer
Amadis Chemical is one of the leading enterprises in medical and health products research,development,manufacture and trading.rnEstablished in 2010, Amadis Chemical are adhering to the " Consummate service Convincing honor " Business strategy. 我們供應商1,4-Dimethylpiperazine-2-carboxylic acid。 The topping products and service we providing to you base on our strong technical accumulation and outstanding professional quality.rnOur associated labs, leading by the outstanding chemistry or pharmacy professors ,make us keep ahead a ...
國家: P.R.China   打電話: +86-571-89925085   傳真: +86-571-89925065

Dayang Chem (Hangzhou) Co.,Ltd.

公司類型: Leading producer
國家: P.R.China
打電話: +86-571-88938639
傳真: +86-571-8893-8652
Hangzhou DayangChem Co. Ltd is a comprehensive entity which specializes in development, production and trade of pharmaceutical, agrochemical and dyestuff intermediates as well as some special type reagents. We have an own factory and share enterprises. We act also as agent of many chemical factories and promote their products to the international market at very competitive price. 我們是賣方1,4-Ditosyl-1,4-diazepan-6-ol。 We take "Credi first, Clients supreme" as our aim. We expect to cooperate with more partners in ...

BOC Sciences

BOC Sciences provides a wide range of customer services, bulk and specialty compounds to the pharmaceutical, agrochemical and biotechnology industries. Tenofovir disoproxil usp related compound h也將會由我們提供。 We intend to offer you the products and services of the highest quality at the most reasonable, cost efficient prices. Most of our compounds can be supplied ranging from mg to kg and arrive with analytic report. We hope to add immense value to your research projects!
公司類型: Supplier
國家: USA
打電話: +1-631-485-4226
傳真: +1-631-614-7828

Safety Information

Hazard Classes:
Storage temperature:
2-8°C

What other providers are available for CAS 521984-48-5?

In addition to the providers presented here for SIS3 hydrochloride with the CAS number 521984-48-5, there are other 3 providers with slightly different product names available for this CAS number.

Leap Chem Co., Ltd | BIOZOL Diagnostica Vertrieb GmbH +1 additional providers that we know from the past




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