Nutlin-3

Description : Nutlin-3 is an MDM2 antagonist, inhibiting p53-Mdm2 interaction (IC50=0.09 µM) via affecting p53 binding pocket of MDM2. It has been studied in anticancer reseaches.

• Molecular Weight :581.49
• Purity :> 98%

Molecular Formula : C30H30Cl2N4O4 Canonical SMILES : CC(C)OC1=C(C=CC(=C1)OC)C2=NC(C(N2C(=O)N3CCNC(=O)C3)C4=CC=C(C=C4)Cl)C5=CC=C(C=C5)Cl InChI : (+/-)-Nutlin-3

+1 additional providers that we know from the past

(−)-Nutlin-3

(±)-4-[4,5-Bis(4-chlorophenyl)-2-(2-isopropoxy-4-methoxy-phenyl)-4,5-dihydro-imidazole-1-carbonyl]-piperazin-2-one

BLD Pharmatech Ltd

4-{[4,5-bis-(4-Chlorophenyl)-2-[4-methoxy-2-(propan-2-yloxy)phenyl]-4,5-dihydro-1H-imidazol-1-yl]carbonyl}piperazin-2-one

+2 additional providers that we know from the past

rel-4-[[(4R,5S)-4,5-bis(4-Chlorophenyl)-4,5-dihydro-2-[4-methoxy-2-(1-methylethoxy)phenyl]-1H-imidazol-1-yl]carbonyl]-2-piperazinone

+2 additional providers that we know from the past