K-7174 (dihydrochloride)

Description : K-7174, one of proteasome inhibitory homopiperazine derivatives, exhibits a therapeutic effect, which is stronger when administered orally than intravenously, without obvious side effects in a murine myeloma model. Moreover, K-7174 kills bortezomib-resistant myeloma cells carrying a β5-subunit mutation in vivo and primary cells from a patient resistant to bortezomib.

• Molecular Weight :641.67
• Purity :> 98%

Molecular Formula : C33H50Cl2N2O6 Canonical SMILES : K-7174

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K-7174, 1,4-bis[5-(3,4,5-trimethoxyphenyl)-4(E)-pentenyl]hexahydro-1H-1,4-diazepine

Leap Chem Co., Ltd

(E,E)-Hexahydro-1,4-bis[5-(3,4,5-trimethoxyphenyl)-4-pentenyl]-1H-1,4-diazepine dihydrochloride

+2 additional providers that we know from the past