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CHIR 99021

BGC Id:314531954527
CAS No:252917-06-9
Synonyms:3-pyridinecarbonitrile,6-[[2-[[4-(2,4-dichlorophenyl)-5-(5-methyl-1h-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]- ; gsk-3 inhibitor xvi ; chir-99021 (ct99021) hcl ; ct99021 ; ct 99021(chir 99021) ; chir-99021, >=98% ; ct 99021 ; chir 99021(ct 99021) ; 3-pyridinecarbonitrile,6-[[2-[[4-(2,4-dichlorophenyl)-5-(4-methyl-1h-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-(9ci) ; chir-99021 ; chir 911, gsk-3 inhibitor xvi ; 6-[2-[4-(2,4-dichlorophenyl)-5-(4-methyl-1h-imidazol-2-yl)pyrimidin-2-ylamino]ethylamino]pyridine-3- ; chir-99021 gsk-3 inhibitor xvi
Molecular Formula:C22H18Cl2N8
Molecular Weight:464.10
EINECS:
Structural Formula

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Description : CHIR-99021 (CT99021) is a glycogen synthase kinase 3β (GSK3β) inhibitor that has antiproliferative activity in vitro and in vivo. It enhances reprogramming of mouse embryonic fibroblasts, transduced by Oct4 and Klf4 only, into iPSCs in combination with tranylcypromine. It also induces cardiomyocyte differentiation from human embryonic stem (ES).
  • Molecular Weight :465.342
  • Purity :> 98%
Molecular Formula : C22H18Cl2N8 Canonical SMILES : CT9902
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