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BGC » Chemicals A-Z » Flavopiridol hydrochloride
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Flavopiridol hydrochloride

BGC Id:962363987687
CAS No:131740-09-5
Synonyms: alvocidib hydrochloride ; flavopiridol hcl ; flavopiridol hci ; hl 275 ; nsc 649890 hcl ; l-86-8276 ; alvocidib hcl ; flavopiridol hydrochloride ; nsc 649890 ; mdl 107826a
Molecular Formula:C21H20ClNO5 HCl
Molecular Weight:438.3
EINECS:
Structural Formula

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Description : Flavopiridol hydrochloride competes with ATP to inhibit CDKs including CDK1, CDK2, CDK4 and CDK6 with IC50 of ~ 40 nM. It is 7.5-fold more selective for CDK1/2/4/6 than CDK7. Flavopiridol is initially found to inhibit EGFR and PKA.
  • Molecular Weight :438.3
  • Boiling Point :603.6ºC at 760 mmHg
  • Melting Point :169.5-170ºC
  • Purity :> 98%
Molecular Formula : C21H20ClNO5.HCl Canonical SMILES : Alvocidib HCL
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