Description:
Meisoindigo is a derivative of indirubin with antitumor activity, which has been used in China for chronic myeloid leukemia. Meisoindigo is an apoptosis inducer and potential agent for the treatment of AML. It inhibits the growth of leukemic cells by inducing marked apoptosis and moderate cell-cycle arrest at the G(0)/G(1) phase.
- Molecular Weight: 276.29
- Molecular Formula: C17H12N2O2
Purity: >98%
Canonical SMILES:
CN1C2=CC=CC=C2C(=C3C4=CC=CC=C4NC3=O)C1=O
InChI:
InChI=1S/C17H12N2O2/c1-19-13-9-5-3-7-11(13)15(17(19)21)14-10-6-2-4-8-12(10)18-16(14)20/h2-9H,1H3,(H,18,20)/b15-14+
InChIKey: QNOCRUSVMMAKSC-CCEZHUSRSA-N
Synonyms:
Methylisoindigotin; N-Methylisoindigotin; (3E)-1-methyl-3-(2-oxo-1H-indol-3-ylidene)indol-2-one
More details are to be found on supplier website
