Description:
Nifuroxazide is a cell-permeable and orally available nitrofuran-based antidiarrheal agent that effectively suppresses the activation of cellular STAT1/3/5 transcription activity with IC50 of 3 μM against IL-6-induced STAT3 activation in U3A cells. It induces apoptosis in breast cancer cells.
- Molecular Weight: 275.22
- Molecular Formula: C12H9N3O5
Purity: >98%
Canonical SMILES:
C1=CC(=CC=C1C(=O)NN=CC2=CC=C(O2)[N+](=O)[O-])O
InChI:
InChI=1S/C12H9N3O5/c16-9-3-1-8(2-4-9)12(17)14-13-7-10-5-6-11(20-10)15(18)19/h1-7,16H,(H,14,17)/b13-7+
InChIKey: YCWSUKQGVSGXJO-NTUHNPAUSA-N
- Boiling Point: N/A
- Appearance: Yellow powder
- Application: broad-spectrum nitrofuran antibiotic
- Storage: Refrigerator, Under Inert Atmosphere
Synonyms:
Nifuroxazid; Dicoferin; Diarlidan; Nifuroxazida; 4-hydroxy-N-[(E)-(5-nitrofuran-2-yl)methylideneamino]benzamide
More details are to be found on supplier website
