Description:
Isoliquiritigenin, a flavonoid from the root of Glycyrrhiza glabrat, inhibits aldose reductase with an IC50 of 320 nM. Isoliquiritigenin is a potent inhibitor of influenza virus replication with an EC50 of 24.7 μm. It has antioxidant, anti-inflammatory, and anti-tumor activities.
- Molecular Weight: 256.25
- Molecular Formula: C15H12O4
Purity: >98%
Canonical SMILES:
C1=CC(=CC=C1C=CC(=O)C2=C(C=C(C=C2)O)O)O
InChI:
InChI=1S/C15H12O4/c16-11-4-1-10(2-5-11)3-8-14(18)13-7-6-12(17)9-15(13)19/h1-9,16-17,19H/b8-3+
InChIKey: DXDRHHKMWQZJHT-FPYGCLRLSA-N
- Boiling Point: 504.0±42.0°C (Predicted)
- Melting Point: >193°C (dec.)
- Solubility: Soluble in Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
- Appearance: Yellow powder
- Application: antidiabetic; antitumour; antioxidant; anti-inflammatory; antimutagenic; antifungal;
- Storage: Store at 2-8°C
Synonyms:
(2E)-1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)-2-propen-1-one; ISL; 2',4,4'-Trihydroxychalcone; GU 17; 6'-deoxychalcone; 2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-(4-hydroxyphenyl)-, (2E)-; trans-2',4,4'-trihydroxychalcone
More details are to be found on supplier website
