Description:
Sulfo-SMCC sodium is a commonly used hetero-bifunctional, noncleavable ADC crosslinker bearing N-hydroxysuccinimide (NHS) ester and maleimide groups to react with primary amines and sulfhydryl groups, respectively.
- Molecular Weight: 436.37
- Molecular Formula: C16H17N2NaO9S
Purity: >98.0%
Canonical SMILES:
C1CC(CCC1CN2C(=O)C=CC2=O)C(=O)ON3C(=O)CC(C3=O)S(=O)(=O)[O-].[Na+]
InChI:
InChI=1S/C16H18N2O9S.Na/c19-12-5-6-13(20)17(12)8-9-1-3-10(4-2-9)16(23)27-18-14(21)7-11(15(18)22)28(24,25)26;/h5-6,9-11H,1-4,7-8H2,(H,24,25,26);/q;+1/p-1
InChIKey: VUFNRPJNRFOTGK-UHFFFAOYSA-M
- Melting Point: > 260 °C (dec.)
- Solubility: 10 mm in DMSO
- Appearance: Off-white powder
- Storage: Store at -20 °C, keep in dry and avoid sunlight.
Synonyms:
Sulfo-SMCC; Sodium 1-((4-((2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl)cyclohexanecarbonyl)oxy)-2,5-dioxopyrrolidine-3-sulfonate
More details are to be found on supplier website
