Description:
9-Aminocamptothecin is a water-insoluble camptothecin derivative and an inhibitor of the nuclear enzyme topoisomerase I, disrupting the repair of single-strand DNA breakages.
- Molecular Weight: 363.37
- Molecular Formula: C20H17N3O4
Purity: >98%
Canonical SMILES:
CCC1(C2=C(COC1=O)C(=O)N3CC4=CC5=C(C=CC=C5N=C4C3=C2)N)O
InChI:
InChI=1S/C20H17N3O4/c1-2-20(26)13-7-16-17-10(6-11-14(21)4-3-5-15(11)22-17)8-23(16)18(24)12(13)9-27-19(20)25/h3-7,26H,2,8-9,21H2,1H3/t20-/m0/s1
InChIKey: FUXVKZWTXQUGMW-FQEVSTJZSA-N
- Boiling Point: 819.6±65.0°C (Predicted)
- Melting Point: 142.0-145.0°C
- Solubility: Soluble in DMSO.
- Appearance: Powder
- Application: Antineoplastic Agents
- Storage: 2-8°C (Protect from light)
Synonyms:
9-amino-camptothecin; 9-amino-CPT; 9-AC; 9-amino-20(S)-camptothecin; 9-amino-20-camptothecin; Aminocamptothecin
More details are to be found on supplier website
