Description:
Vismodegib (GDC-0449) is a potent, novel and specific inhibitor of hedgehog with IC50 of 3 nM and also inhibitor of P-gp with IC50 of 3.0 μM.
- Molecular Weight: 421.292
- Molecular Formula: C19H14Cl2N2O3S
Purity: 0.99
Canonical SMILES:
CS(=O)(=O)C1=CC(=C(C=C1)C(=O)NC2=CC(=C(C=C2)Cl)C3=CC=CC=N3)Cl
InChI:
InChI=1S/C19H14Cl2N2O3S/c1-27(25,26)13-6-7-14(17(21)11-13)19(24)23-12-5-8-16(20)15(10-12)18-4-2-3-9-22-18/h2-11H,1H3,(H,23,24)
InChIKey: BPQMGSKTAYIVFO-UHFFFAOYSA-N
- Appearance: white solid powder
Synonyms:
Code name: GDC-0449; GDC 0449; GDC0449; RG3616; RG 3616; RG-3616. trade name: Erivedge.
More details are to be found on supplier website
