CAS No. 863031-21-4

Description	White or almost white crystal powder
Identification	Meets the requirements
Water	Not more than 2.0%
Residue on Ignition	Not more than 0.2%
Heavy Metals	Not more than 20ppm
Loss on drying	Not more than 1.0%
Related substances
Individual impurity	Not more than 0.5%
Total impurities	Not more than 2.0%
Assay (on the dried basis)	98.0%~102.0%

Molecular Formula: C30H24N4O8
Molecular Weight: 568.53356

Description:
Azilsartan Medoxomil is a potent angiotensin II type 1 (AT1) receptor antagonist that inhibits the RAAS, with an IC50 of 2.6 nM. It exhibits more than 10,000-fold selectivity over AT2. Azilsartan Medoxomil can be used for the treatment of mild to moderate essential hypertension.

• Molecular Weight: 568.53
• Molecular Formula: C30H24N4O8

Purity: >98%

Canonical SMILES:
CCOC1=NC2=CC=CC(=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NC(=O)ON5)C(=O)OCC6=C(OC(=O)O6)C

InChI:
InChI=1S/C30H24N4O8/c1-3-38-28-31-23-10-6-9-22(27(35)39-16-24-17(2)40-30(37)41-24)25(23)34(28)15-18-11-13-19(14-12-18)20-7-4-5-8-21(20)26-32-29(36)42-33-26/h4-14H,3,15-16H2,1-2H3,(H,32,33,36)

InChIKey: QJFSABGVXDWMIW-UHFFFAOYSA-N

• Boiling Point: 748.0±70.0 °C at 760 mmHg
• Melting Point: 212-214 °C
• Solubility: Water: practically insoluble
• Appearance: -
• Application: the treatment of mild to moderate essential hypertension

Synonyms:
TAK-491 Medoxomil; TAK491 Medoxomil; Edarbi; 863031-21-4; Azilsartan (medoxomil); TAK 491; UNII-LL0G25K7I2

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