Description:
(-)-Blebbistatin is a cell-permeable inhibitor for non muscle myosin II ATPase with IC50 of ~2 μM, does not inhibit myosin light chain kinase, inhibits contraction of the cleavage furrow without disrupting mitosis or contractile ring assembly.
- Molecular Weight: 292.33
- Molecular Formula: C18H16N2O2
Purity: >98%
Canonical SMILES:
CC1=CC2=C(C=C1)N=C3C(C2=O)(CCN3C4=CC=CC=C4)O
InChI:
InChI=1S/C18H16N2O2/c1-12-7-8-15-14(11-12)16(21)18(22)9-10-20(17(18)19-15)13-5-3-2-4-6-13/h2-8,11,22H,9-10H2,1H3/t18-/m1/s1
InChIKey: LZAXPYOBKSJSEX-GOSISDBHSA-N
- Boiling Point: 486.7±55.0 °C at 760 mmHg
- Solubility: DMSO: soluble5mg/mL
- Storage: Desiccate at +4°C
Synonyms:
(S)-(-)-Blebbistatin; (S)-blebbistatin; (3aS)-3a-hydroxy-6-methyl-1-phenyl-2,3-dihydropyrrolo[2,3-b]quinolin-4-one
More details are to be found on supplier website
